{"id":"W4390544729","doi":"10.21203/rs.3.rs-3751380/v1","title":"Ketone Esters partially and selectively rescue mitochondrial bioenergetics after acute cervical spinal cord injury in rats: A time-course","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Spinal Cord Injury Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Rick Hansen Foundation","keywords":"Bioenergetics; Spinal cord injury; Spinal cord; Spinal injury; Mitochondrion; Ketone bodies; Energy metabolism; Medicine; Anesthesia; Chemistry; Internal medicine; Biology; Neuroscience; Metabolism; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001953082,0.0007609059,0.00087882,0.0004113976,0.0001925063,0.0003712501,0.0004304246,0.0005648053,0.003090012],"category_scores_gemma":[0.0002410015,0.0001897228,0.0005798581,0.0003499408,0.0005465591,0.0007385112,0.0002657469,0.0009552253,0.0006073375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002584774,"about_ca_system_score_gemma":0.0007253471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001766461,"about_ca_topic_score_gemma":0.00382871,"domain_scores_codex":[0.9998683,0.00001167129,0.00001333365,0.0000237499,0.00001647164,0.00006646597],"domain_scores_gemma":[0.9997602,0.00002914116,0.00005270989,0.00004832606,0.00004041133,0.00006924204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02763558,0.001138302,0.0003446672,0.000327168,0.00007884861,0.0002444598,0.00009066389,0.0003372322,0.9560833,0.0002282411,0.0004248004,0.01306665],"study_design_scores_gemma":[0.000602919,0.007317199,0.003955052,0.00002572665,0.0001856197,0.0001674294,0.0001700119,0.0003455034,0.9849901,0.0001853188,0.002027694,0.00002737368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946641,0.00215714,0.001106639,0.0001790924,0.0001248739,0.00006706821,0.0007240582,0.0001061509,0.0008709638],"genre_scores_gemma":[0.9862795,0.003252469,0.001273827,0.00009744913,0.00004275975,0.00010802,0.0009999815,0.0000439086,0.007902182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003090012,"threshold_uncertainty_score":0.01033717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04880973530408072,"score_gpt":0.4447886020012511,"score_spread":0.3959788666971704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}