{"id":"W4390545789","doi":"10.1016/j.pathol.2023.12.412","title":"Predictive and prognostic biomarkers in gastrointestinal tract tumours","year":2024,"lang":"en","type":"article","venue":"Pathology","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital; University Health Network","funders":"","keywords":"Gastrointestinal tract; Medicine; Immunohistochemistry; Pathology; Gastrointestinal cancer; Internal medicine; Gastrointestinal pathology; Gastroenterology; Oncology; Cancer; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007217148,0.00007767815,0.0001447396,0.0000943422,0.00001812328,0.000006616993,0.00001229556,0.00001987492,0.00002178297],"category_scores_gemma":[0.00009771736,0.00005738909,0.00002323037,0.00009925687,0.0001035744,0.00002172301,0.00001959862,0.00009608528,0.000007546925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005254765,"about_ca_system_score_gemma":0.00004276235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002004415,"about_ca_topic_score_gemma":0.00003081711,"domain_scores_codex":[0.9995006,0.0000216647,0.00008810189,0.0001979995,0.00004542309,0.0001461524],"domain_scores_gemma":[0.9997945,0.0001009305,0.000009399168,0.00004212589,0.00001372617,0.00003928531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000223348,0.0001010846,0.9810029,0.00006935233,0.00002894945,0.007280748,0.0006737292,4.079101e-7,0.0005903991,0.00006429174,0.000165968,0.009798821],"study_design_scores_gemma":[0.0004725584,0.001567264,0.9912878,0.0002608446,0.00006997211,0.005382223,0.0002798425,0.0003142669,0.00003005281,0.0001826817,0.0001105769,0.00004196878],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906984,0.003884058,0.00005702209,0.001127517,0.00007726289,0.000240874,0.000011743,0.0000513607,0.003851786],"genre_scores_gemma":[0.9993182,0.00007010445,0.0003735449,0.00004657947,0.00003821654,0.0000630474,0.000005619937,0.00000755234,0.00007717055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01028485,"threshold_uncertainty_score":0.2340259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01472120283526128,"score_gpt":0.2878482367641194,"score_spread":0.2731270339288581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}