{"id":"W4390561393","doi":"10.1111/myc.13683","title":"Treatment of onychomycosis in an era of antifungal resistance: Role for antifungal stewardship and topical antifungal agents","year":2024,"lang":"en","type":"article","venue":"Mycoses","topic":"Nail Diseases and Treatments","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mediprobe Research (Canada); University of Toronto","funders":"","keywords":"Itraconazole; Terbinafine; Fluconazole; Antifungal drug; Trichophyton; Antifungal; Drug resistance; Amphotericin B; Antifungal drugs; Medicine; Dermatophyte; Posaconazole; Dermatology; Microbiology; Biology; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007172745,0.0002143032,0.0005403684,0.0001511959,0.00003969083,0.00003040449,0.00005974182,0.00009709194,0.00009787992],"category_scores_gemma":[0.00004090435,0.0001675857,0.0001841641,0.0002022043,0.00008115752,0.0001270753,0.00002046823,0.00007257368,0.000003016838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009048607,"about_ca_system_score_gemma":0.0001304118,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001148196,"about_ca_topic_score_gemma":0.00008631645,"domain_scores_codex":[0.9986446,0.00004814319,0.000391885,0.0004111961,0.0002382515,0.0002659622],"domain_scores_gemma":[0.9992759,0.0001473652,0.00006161533,0.0002869056,0.00007122012,0.0001569618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002233946,0.002865095,0.9355685,0.001210118,0.0004008875,0.0002579459,0.0005856432,0.00000131466,0.01497976,0.0008852732,0.0004203994,0.04059116],"study_design_scores_gemma":[0.00469273,0.002976235,0.9584566,0.000754378,0.0005744211,0.0000165347,0.0002639669,0.0003559218,0.02827024,0.0004614698,0.002994088,0.0001834567],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868457,0.01104248,0.00001301368,0.0001342214,0.0001602055,0.0007220121,0.0005163216,0.00003705614,0.0005290211],"genre_scores_gemma":[0.9975465,0.0007817898,0.0007761392,0.00002051565,0.0001008525,0.00006142096,0.0001219542,0.00002990625,0.0005609111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0404077,"threshold_uncertainty_score":0.6833946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0296174265832026,"score_gpt":0.332115641434572,"score_spread":0.3024982148513694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}