{"id":"W4390605485","doi":"10.1007/s12033-023-01007-3","title":"Improved Manufacturing Methods of Extracellular Vesicles Pseudotyped with the Vesicular Stomatitis Virus Glycoprotein","year":2024,"lang":"en","type":"article","venue":"Molecular Biotechnology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; PROTEO; National Research Council Canada; Université du Québec à Montréal; Natural Sciences and Engineering Research Council of Canada","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Transfection; Vesicular stomatitis virus; Biology; Cell culture; Virus; Virology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000530548,0.000383966,0.0003141699,0.0001791987,0.0001098749,0.00006149526,0.0007546193,0.0005580656,0.00003626996],"category_scores_gemma":[0.00009341416,0.0002849877,0.0002300798,0.0003257126,0.0006601852,0.000009809154,0.0003396023,0.0004044363,0.00001688468],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003015791,"about_ca_system_score_gemma":0.0001264296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004673899,"about_ca_topic_score_gemma":0.00002225594,"domain_scores_codex":[0.9978467,0.0002716274,0.0003873025,0.0007846007,0.0002253168,0.0004844931],"domain_scores_gemma":[0.9983098,0.00003845439,0.0001501097,0.001350121,0.00005925059,0.00009229295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008558574,0.00006143712,0.000004249002,0.000125032,0.0002979031,0.0002297015,0.00003035917,0.00008467175,0.9637536,0.002260374,0.0001761879,0.03289093],"study_design_scores_gemma":[0.0003452001,0.0004454754,0.00003454458,0.00005681459,0.0001341392,0.0001565391,0.00007768589,0.0008707911,0.9675494,0.0005314061,0.02944974,0.0003482035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6943272,0.02387663,0.279521,0.001351663,0.0001093418,0.0005327633,0.00002414498,0.0001534266,0.0001037661],"genre_scores_gemma":[0.9564379,0.0002130304,0.04262717,0.000135197,0.00006706305,0.0001101712,0.00004933296,0.0001113692,0.0002487171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2621107,"threshold_uncertainty_score":0.9999602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005121172439796589,"score_gpt":0.2539204641782438,"score_spread":0.2487992917384472,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}