{"id":"W4390608015","doi":"10.3390/cells13020108","title":"A High-Protein Diet Promotes Atrial Arrhythmogenesis via Absent-in-Melanoma 2 Inflammasome","year":2024,"lang":"en","type":"article","venue":"Cells","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; European Commission; American Heart Association","keywords":"Inflammasome; AIM2; Pathogenesis; Endoplasmic reticulum; Myocyte; Chemistry; Caspase 1; Signal transducing adaptor protein; Downregulation and upregulation; Endocrinology; Inflammation; Cancer research; Internal medicine; Medicine; Cell biology; Biology; Signal transduction; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001786903,0.0004517559,0.0004490688,0.0003499155,0.0001912901,0.0003669275,0.0001456497,0.0004882423,0.001506515],"category_scores_gemma":[0.0001506666,0.0001935556,0.0005828767,0.000153611,0.00029411,0.0003682509,0.0003458318,0.001183275,0.0002055775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001426571,"about_ca_system_score_gemma":0.0002028413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002156149,"about_ca_topic_score_gemma":0.0004381953,"domain_scores_codex":[0.999827,0.00002853552,0.00002759187,0.0000435153,0.00002829732,0.00004519251],"domain_scores_gemma":[0.9998717,0.000009339139,0.00004811952,0.0000112017,0.00001298676,0.00004652806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003095211,0.000626037,0.002362509,0.0002494521,0.00006360011,0.000248919,0.00005198742,0.00005541426,0.9893681,0.0001246042,0.0001768845,0.003577172],"study_design_scores_gemma":[0.001302999,0.01572992,0.1786432,0.0001634987,0.0005585141,0.00227751,0.0004911541,0.003587456,0.7829704,0.001044783,0.0131413,0.0000894464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944273,0.002491722,0.001652223,0.0002710477,0.00009488953,0.00004233919,0.0003083697,0.00008147888,0.000630696],"genre_scores_gemma":[0.9936327,0.001886263,0.001819981,0.0003114184,0.00004096362,0.0001338569,0.0004426325,0.00001811172,0.001713992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001506515,"threshold_uncertainty_score":0.005039752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004034503517411966,"score_gpt":0.2040545741521624,"score_spread":0.2000200706347505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}