{"id":"W4390608015","doi":"10.3390/cells13020108","title":"A High-Protein Diet Promotes Atrial Arrhythmogenesis via Absent-in-Melanoma 2 Inflammasome","year":2024,"lang":"en","type":"article","venue":"Cells","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; European Commission; American Heart Association","keywords":"Inflammasome; AIM2; Pathogenesis; Endoplasmic reticulum; Myocyte; Chemistry; Caspase 1; Signal transducing adaptor protein; Downregulation and upregulation; Endocrinology; Inflammation; Cancer research; Internal medicine; Medicine; Cell biology; Biology; Signal transduction; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001636897,0.0002164858,0.0001852205,0.00009471287,0.00004709932,0.00006006798,0.0001694499,0.0002054949,0.0001203307],"category_scores_gemma":[0.00002275773,0.0002056973,0.000205668,0.0001651806,0.00005760724,0.000008170662,0.0001061362,0.000119074,0.0003136427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000199463,"about_ca_system_score_gemma":0.00008391163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005761027,"about_ca_topic_score_gemma":0.00004899984,"domain_scores_codex":[0.998744,0.00005067043,0.0002906152,0.000430193,0.0001174803,0.0003670255],"domain_scores_gemma":[0.9995234,0.00001077471,0.00004133761,0.0003408545,0.00002969292,0.00005395737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001867219,0.0000226279,0.0001365299,0.00007814528,0.00007612099,0.00007221787,0.00007130471,0.00006985508,0.9925271,0.00008730022,0.0004864047,0.006185649],"study_design_scores_gemma":[0.0006750444,0.0004096917,0.0005863171,0.00005485713,0.00002288864,0.000004742142,0.00003734068,0.0001169992,0.9421457,0.0003250366,0.05528608,0.0003352716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933316,0.004549861,0.0001742107,0.0002084177,0.0007276605,0.0003971433,0.0000175148,0.00003735712,0.0005562826],"genre_scores_gemma":[0.9966149,0.0002269224,0.0002494415,0.00004497648,0.0007897457,0.00004372283,0.000137191,0.00004609237,0.001847001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05479967,"threshold_uncertainty_score":0.8388091,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004034503517411966,"score_gpt":0.2040545741521624,"score_spread":0.2000200706347505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}