{"id":"W4390631596","doi":"10.1158/1055-9965.epi-23-0613","title":"Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies","year":2024,"lang":"en","type":"article","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Ontario; Lunenfeld-Tanenbaum Research Institute; Princess Margaret Cancer Centre; University of British Columbia; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"National Center for Research Resources; Common Fund; National Institute of Environmental Health Sciences; Division of Cancer Epidemiology and Genetics, National Cancer Institute; National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Institute on Drug Abuse; National Heart, Lung, and Blood Institute; National Institute of Mental Health; NIH Office of the Director; National Institute on Aging; Cancer Prevention and Research Institute of Texas; National Natural Science Foundation of China; U.S. Department of Health and Human Services; National Institutes of Health; National Human Genome Research Institute; World Health Organization","keywords":"Genome-wide association study; Lung cancer; Medicine; Population; Cancer; Oncology; Demography; Internal medicine; Environmental health; Biology; Genetics; Single-nucleotide polymorphism; Genotype; Sociology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001891283,0.0003620297,0.0006456234,0.0010159,0.0004914533,0.001282332,0.0004814858,0.0006783837,0.001388406],"category_scores_gemma":[0.00314491,0.0002700818,0.001090237,0.001568848,0.0005064093,0.0003851989,0.0009513724,0.0007392653,0.0001459875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001670381,"about_ca_system_score_gemma":0.0002298225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002600883,"about_ca_topic_score_gemma":0.00527504,"domain_scores_codex":[0.9987249,0.0002705719,0.0001571484,0.0005247819,0.0002194186,0.0001031476],"domain_scores_gemma":[0.9975652,0.00080147,0.0006705304,0.0004542341,0.0002421519,0.0002664352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003274346,0.00001752717,0.9919541,0.00005799634,0.001391757,0.0001730198,0.0001444977,0.0000639953,0.002190159,0.00006292472,0.00007459871,0.003541944],"study_design_scores_gemma":[0.00001371222,0.00005442333,0.9978855,0.00001628267,0.0007266912,0.0003865937,0.00008946778,0.0001542354,0.0002243703,0.000111675,0.0003319025,0.000005202829],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952944,0.003177475,0.0006989769,0.0001077341,0.00001851895,0.000009794258,0.000321674,0.00002048528,0.0003509445],"genre_scores_gemma":[0.9989221,0.0004755724,0.0002503393,0.00004261392,0.00001655074,0.000005960363,0.0002178087,0.000007099902,0.00006207524],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002600883,"threshold_uncertainty_score":0.0100022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05310434667444801,"score_gpt":0.4138759137916952,"score_spread":0.3607715671172472,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}