{"id":"W4390638306","doi":"10.1115/1.4064436","title":"Enhancing Inhalation Drug Delivery: A Comparative Study and Design Optimization of a Novel Valved Holding Chamber","year":2024,"lang":"en","type":"article","venue":"Journal of Biomechanical Engineering","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Inhalation; Drug delivery; Drug; Medicine; Pharmacology; Computer science; Anesthesia; Materials science; Nanotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007586844,0.0001180594,0.0003424502,0.0004671947,0.00002642829,0.00002853892,0.00003045713,0.00005982693,0.00001627623],"category_scores_gemma":[0.00007279193,0.00009496356,0.00008957007,0.0003810269,0.00001233095,0.0002060741,0.00002504726,0.0002220958,8.632347e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000767935,"about_ca_system_score_gemma":0.00007718723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002562081,"about_ca_topic_score_gemma":3.71449e-7,"domain_scores_codex":[0.9989113,0.00003423591,0.0005448376,0.0001189417,0.0002754093,0.0001152548],"domain_scores_gemma":[0.9993198,0.0001605547,0.0001446888,0.00006405501,0.0002059821,0.0001049254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0001451594,0.0002474375,0.00001955697,0.0002008013,0.0002774729,0.00007982091,0.002294014,0.1955569,0.8004562,0.0000609001,0.00001728304,0.0006444132],"study_design_scores_gemma":[0.001225571,0.0004281273,0.00007506975,0.0007303967,0.0001679403,0.0001874325,0.0006220285,0.9052449,0.09119945,0.000001906096,0.00002422888,0.00009293325],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5479966,0.0003999651,0.4511867,0.00003586473,0.0001858867,0.0001684036,8.269232e-7,0.0000196102,0.000006131549],"genre_scores_gemma":[0.976229,0.00003511101,0.02355302,0.00001636434,0.0001340567,0.000002140742,9.567156e-7,0.00001666383,0.00001266928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.709688,"threshold_uncertainty_score":0.3872502,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03692216364132197,"score_gpt":0.2878612815643817,"score_spread":0.2509391179230598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}