{"id":"W4390640019","doi":"10.1016/j.bja.2023.11.050","title":"Pharmacological agents for procedural sedation and analgesia in the emergency department and intensive care unit: a systematic review and network meta-analysis of randomised trials","year":2024,"lang":"en","type":"review","venue":"British Journal of Anaesthesia","topic":"Intensive Care Unit Cognitive Disorders","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sinai Health System; University of Ottawa; University of Toronto; McMaster University; Impact","funders":"","keywords":"Medicine; Sedation; Emergency department; Ketamine; Midazolam; Meta-analysis; Propofol; Confidence interval; Adverse effect; MEDLINE; Intensive care unit; Randomized controlled trial; Anesthesia; Systematic review; Emergency medicine; Intensive care medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009981148,0.003029627,0.02149187,0.004952963,0.0007138661,0.003467354,0.002357177,0.002549284,0.005389003],"category_scores_gemma":[0.03070043,0.001729882,0.0304555,0.005242874,0.0009491674,0.002172621,0.002220015,0.003061902,0.0004392151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00350854,"about_ca_system_score_gemma":0.003721612,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007956751,"about_ca_topic_score_gemma":0.02123887,"domain_scores_codex":[0.991557,0.003598346,0.00278104,0.0008934698,0.0008331793,0.0003368481],"domain_scores_gemma":[0.9829096,0.01261768,0.003096115,0.0004550335,0.0006867303,0.0002348131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.003264827,0.00003357942,0.001160005,0.4700556,0.5119982,0.00008967271,0.00007895632,0.0003718452,0.0002029057,0.0001142442,0.0005270855,0.012103],"study_design_scores_gemma":[0.001890724,0.0002015506,0.002044078,0.03186744,0.9617521,0.00008843401,0.00005355953,0.000110941,0.00009679261,0.0002290545,0.001634189,0.00003102062],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003201053,0.9953816,0.0004474607,0.0001168006,0.0001389774,0.0002455781,0.0003056855,0.00002066803,0.0001421021],"genre_scores_gemma":[0.09194952,0.9028245,0.002485219,0.0009056662,0.0001808933,0.0007763317,0.0004842539,0.00003615861,0.0003574913],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02149187,"threshold_uncertainty_score":0.05278593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1653106318734988,"score_gpt":0.4265338932354676,"score_spread":0.2612232613619687,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}