{"id":"W4390645750","doi":"10.26508/lsa.202302409","title":"Centriole and transition zone structures in photoreceptor cilia revealed by cryo-electron tomography","year":2024,"lang":"en","type":"article","venue":"Life Science Alliance","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"National Eye Institute; National Institute of Mental Health; National Institutes of Health; Welch Foundation","keywords":"Cilium; Cryo-electron tomography; Basal body; Electron tomography; Biology; Motile cilium; Cell biology; Centriole; Ciliopathies; Microtubule; Biophysics; Axoneme; Ciliogenesis; Ultrastructure; Flagellum; Anatomy; Transmission electron microscopy; Nanotechnology; Tomography; Physics; Materials science; Scanning transmission electron microscopy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001451444,0.0001168223,0.00009144675,0.00005067672,0.00007478006,0.00007799687,0.0001733882,0.00006029341,0.00002309103],"category_scores_gemma":[0.00006318733,0.0001074593,0.00003761724,0.0004051259,0.0002980173,0.00001343946,0.00002684455,0.00006594061,0.000003931439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001280667,"about_ca_system_score_gemma":0.00019884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002274897,"about_ca_topic_score_gemma":0.00001379233,"domain_scores_codex":[0.9988753,0.00002374192,0.0001291527,0.0004882194,0.000178611,0.0003050427],"domain_scores_gemma":[0.9995981,0.000006878434,0.00001948686,0.000155371,0.00003039814,0.0001897972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003778146,0.000020265,0.001376954,0.00002987841,0.000007022621,0.000002188428,0.00008925339,0.0000166249,0.9905002,0.00003475257,0.006759221,0.001125908],"study_design_scores_gemma":[0.0006670273,0.0003555076,0.03674945,0.0001437452,0.00002291389,0.00001076896,0.0001867936,0.0007073753,0.8869178,0.0005533135,0.07320814,0.0004771177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9809852,0.01756416,0.0004646362,0.000446027,0.0001707303,0.0001647418,0.00005855543,0.00001643604,0.0001295318],"genre_scores_gemma":[0.9970518,0.001566719,0.0003809019,0.0006365166,0.00008510741,0.00001768015,0.00004189053,0.000008425318,0.0002109724],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1035823,"threshold_uncertainty_score":0.4382061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003389858968105771,"score_gpt":0.2333358990700375,"score_spread":0.2299460401019317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}