{"id":"W4390668354","doi":"10.3390/cells13020113","title":"An Examination of the Effect of Aspirin and Salicylic Acid on Soluble Fms-like Tyrosine Kinase-1 Release from Human Placental Trophoblasts","year":2024,"lang":"en","type":"article","venue":"Cells","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Child Health and Human Development; National Institutes of Health; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Grand Challenges Canada; Bill and Melinda Gates Foundation; Queen's University; Department for International Development; United States Agency for International Development","keywords":"Salicylic acid; Aspirin; Trophoblast; Preeclampsia; Messenger RNA; Metabolite; Biology; Hypoxia (environmental); Tyrosine; Mechanism of action; Tyrosine kinase; Pharmacology; Placenta; Andrology; Endocrinology; Chemistry; Internal medicine; Biochemistry; Fetus; Signal transduction; Medicine; In vitro; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002561998,0.000291116,0.0003646709,0.0001933304,0.0001727634,0.0002112961,0.000118674,0.0002712097,0.001481313],"category_scores_gemma":[0.0002467259,0.0001730372,0.0004380241,0.0002301108,0.0001962141,0.0001963913,0.0001278723,0.0004113331,0.0002705284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001705814,"about_ca_system_score_gemma":0.0001825954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008562494,"about_ca_topic_score_gemma":0.001310548,"domain_scores_codex":[0.9997995,0.0000510281,0.00002738505,0.0000319452,0.00004958786,0.00004047846],"domain_scores_gemma":[0.9998528,0.00005591985,0.00002558913,0.00002002189,0.00001880774,0.00002679665],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009954759,0.00005961832,0.000574921,0.0001000881,0.00001660874,0.0001108418,0.00006693263,0.00003084524,0.9961366,0.00002190215,0.00003028403,0.001855911],"study_design_scores_gemma":[0.00008670285,0.004300797,0.04904101,0.00001406938,0.0000782338,0.0004529611,0.0001601828,0.0006068912,0.9421818,0.00003791768,0.003028782,0.00001058543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925578,0.004793412,0.0006330258,0.0001262103,0.00004246231,0.00004025975,0.0004288237,0.0000143081,0.001363808],"genre_scores_gemma":[0.9919877,0.002844949,0.001339259,0.00009172232,0.00003582777,0.00006930375,0.0007406023,0.000006994273,0.002883665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001481313,"threshold_uncertainty_score":0.00495553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01008380568506763,"score_gpt":0.2558682962351507,"score_spread":0.2457844905500831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}