{"id":"W4390672483","doi":"10.1021/acsomega.3c08184","title":"Role of the Gut Bacteria-Derived Metabolite Phenylacetylglutamine in Health and Diseases","year":2024,"lang":"en","type":"review","venue":"ACS Omega","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Government of Saskatchewan; JSS Academy of Higher Education and Research; College of Pharmacy and Nutrition, University of Saskatchewan; JSS College of Pharmacy; University of Nebraska Medical Center","keywords":"Metabolite; Gut flora; Glutamine; Biology; Biochemistry; Receptor; Phenylacetic acid; Amino acid; Microbiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002872786,0.0005874953,0.0007872529,0.001199851,0.0002645161,0.0008174735,0.0004632944,0.0008257063,0.004377442],"category_scores_gemma":[0.0004621362,0.0001620424,0.0003447554,0.00109479,0.0002729243,0.0008009467,0.0006483803,0.001449165,0.002016862],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000489732,"about_ca_system_score_gemma":0.0008438741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007673633,"about_ca_topic_score_gemma":0.001515214,"domain_scores_codex":[0.9998944,0.00002173496,0.0000129431,0.00001843205,0.00003781283,0.00001472017],"domain_scores_gemma":[0.9998716,0.00005075043,0.00001695377,0.000004027361,0.00003653235,0.00002021182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009890713,0.00006130738,0.0002472976,0.01523673,0.00009856297,0.0002697813,0.00008159243,0.0003153822,0.003582046,0.006171676,0.04996944,0.9238672],"study_design_scores_gemma":[0.000008439699,0.00006962214,0.0006172784,0.001855767,0.00006161343,0.0007394122,0.00004455188,0.00005690349,0.0004409387,0.002029831,0.9940647,0.00001093846],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001522902,0.997497,0.0001214657,0.0003871839,0.000361434,0.000002766521,0.00002331356,0.00001093725,0.001443609],"genre_scores_gemma":[0.001076948,0.9973044,0.000123736,0.0002264903,0.0002331047,0.00000440549,0.00003245424,0.00000168392,0.0009967333],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004377442,"threshold_uncertainty_score":0.01464403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01370377013806289,"score_gpt":0.3012931060043741,"score_spread":0.2875893358663112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}