{"id":"W4390672483","doi":"10.1021/acsomega.3c08184","title":"Role of the Gut Bacteria-Derived Metabolite Phenylacetylglutamine in Health and Diseases","year":2024,"lang":"en","type":"review","venue":"ACS Omega","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Government of Saskatchewan; JSS Academy of Higher Education and Research; College of Pharmacy and Nutrition, University of Saskatchewan; JSS College of Pharmacy; University of Nebraska Medical Center","keywords":"Metabolite; Gut flora; Glutamine; Biology; Biochemistry; Receptor; Phenylacetic acid; Amino acid; Microbiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001429602,0.000270262,0.000855537,0.0000745218,0.00003865846,0.00002114003,0.0002438018,0.0001913229,0.00000250782],"category_scores_gemma":[0.00004451818,0.0001721243,0.00020642,0.0001923447,0.00008368253,0.000002170713,0.0003041886,0.0001836037,0.000004863105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002544435,"about_ca_system_score_gemma":0.0006312719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005135912,"about_ca_topic_score_gemma":0.0000444911,"domain_scores_codex":[0.9985978,0.0001869225,0.0004879424,0.0003891994,0.00006983691,0.000268284],"domain_scores_gemma":[0.9991749,0.00001317963,0.0002297408,0.0004498379,0.00002132174,0.0001110273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004415943,0.0002213594,0.0001730404,0.07544464,0.0004883859,0.000003473921,0.0003076341,2.86645e-7,0.1064383,0.0003825374,0.003265687,0.8132305],"study_design_scores_gemma":[0.0001427825,0.00006087891,0.0003905642,0.002189515,0.0001623834,0.00001494464,0.00002818457,2.022707e-7,0.0001454421,0.00002622361,0.9966837,0.0001552119],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01094333,0.9878197,3.928871e-7,0.0001102949,0.0001543098,0.0004980454,0.0004298601,0.000005980965,0.00003810372],"genre_scores_gemma":[0.00481722,0.9938641,0.00003940779,0.0001787635,0.0001520746,0.00003397408,0.0003866897,0.00004100143,0.0004867709],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.993418,"threshold_uncertainty_score":0.7019025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01370377013806289,"score_gpt":0.3012931060043741,"score_spread":0.2875893358663112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}