{"id":"W4390678547","doi":"10.1002/9781119823193.ch15","title":"Familial Myeloid Neoplasms—When to Suspect and What to Do?","year":2023,"lang":"en","type":"other","venue":"","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Dalhousie University; Provincial Health Services Authority","funders":"","keywords":"Germline; Medicine; Genetic testing; Myeloid; Myelodysplastic syndromes; Myeloid leukemia; Germline mutation; Myeloproliferative neoplasm; Immunology; Genetics; Internal medicine; Mutation; Biology; Myelofibrosis; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001580134,0.0005014968,0.0007419788,0.001426648,0.001580679,0.002035835,0.0007981411,0.002751251,0.008871255],"category_scores_gemma":[0.008486932,0.0002498711,0.0003603347,0.0006139196,0.001601063,0.004655309,0.001115448,0.003051161,0.005407787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001050744,"about_ca_system_score_gemma":0.001598743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002839894,"about_ca_topic_score_gemma":0.006423404,"domain_scores_codex":[0.9993826,0.0002138528,0.0001045252,0.0000516001,0.0001731715,0.0000741465],"domain_scores_gemma":[0.9980685,0.0007588911,0.0002187806,0.00006448735,0.0005488466,0.0003404513],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008755379,0.0001588591,0.01363214,0.0008019743,0.00001970096,0.01190102,0.001144104,0.0002561857,0.0007711151,0.01938862,0.4426815,0.5091572],"study_design_scores_gemma":[0.00005423497,0.0001377706,0.008687722,0.01054979,0.00005267553,0.09269454,0.01203965,0.0004162258,0.0005944626,0.0617808,0.8128927,0.00009936249],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.01028671,0.1835277,0.013154,0.63368,0.0176318,0.0002588991,0.0003355365,0.0005101076,0.1406151],"genre_scores_gemma":[0.1115073,0.5249779,0.05025084,0.2096468,0.0377781,0.0004470809,0.001096168,0.0004304868,0.06386538],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.008871255,"threshold_uncertainty_score":0.02967733,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01852222053871618,"score_gpt":0.3027896925482579,"score_spread":0.2842674720095418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}