{"id":"W4390691899","doi":"10.21203/rs.3.rs-3654691/v1","title":"Cyclopropanes to Spirocyclic Amine-Boranes: Merging Metal Free C‒H Bond Activation and C‒C Bond Cleavage","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Cyclopropane Reaction Mechanisms","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Université de Montréal; University of Alberta; Centre in Green Chemistry and Catalysis","keywords":"Bond cleavage; Boranes; Chemistry; Amine gas treating; Cleavage (geology); Stereochemistry; Metal; Single bond; Organic chemistry; Materials science; Catalysis; Boron","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003004906,0.0004337954,0.0001670306,0.0001767465,0.000116396,0.0002468099,0.000264582,0.0002602936,0.002071877],"category_scores_gemma":[0.0001902184,0.0001647038,0.00019078,0.0001244541,0.0003187,0.0004122619,0.0003386149,0.0005971466,0.0006450954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001923703,"about_ca_system_score_gemma":0.0002179576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001800606,"about_ca_topic_score_gemma":0.0003463872,"domain_scores_codex":[0.999818,0.00003025658,0.00001386942,0.00004706834,0.0000358606,0.00005493848],"domain_scores_gemma":[0.9999266,0.00001882145,0.00002286263,0.00001094246,0.000007995921,0.00001283393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001909688,0.00008999484,0.000262242,0.0003721818,0.00002719689,0.0003487174,0.0000989394,0.0007002148,0.9846876,0.004156689,0.0003711813,0.008694047],"study_design_scores_gemma":[0.00003237748,0.0004864102,0.0005169589,0.00001784242,0.00001206938,0.0003676904,0.00002143612,0.001260449,0.9898077,0.0005230546,0.006941488,0.00001260087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9073796,0.008223329,0.05246591,0.0006015644,0.0002974921,0.0002315597,0.0003119504,0.0004688379,0.03001976],"genre_scores_gemma":[0.9886628,0.001633636,0.006676739,0.00008213382,0.00002403367,0.00003658265,0.0001073433,0.00002468224,0.00275196],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002071877,"threshold_uncertainty_score":0.006931126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04395633399606106,"score_gpt":0.3597018234101118,"score_spread":0.3157454894140507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}