{"id":"W4390696292","doi":"10.3390/cancers16020292","title":"The Tumor Suppressor SOCS1 Diminishes Tolerance to Oxidative Stress in Hepatocellular Carcinoma","year":2024,"lang":"en","type":"article","venue":"Cancers","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Alliance de recherche numérique du Canada","keywords":"Suppressor of cytokine signaling 1; Oxidative stress; Reactive oxygen species; HEPA; Chemistry; Cancer research; Biology; Cell biology; Biochemistry; Suppressor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008683651,0.0001143572,0.0001590488,0.00007115844,0.00008729644,0.0000680349,0.0000990677,0.00002523236,0.0001684317],"category_scores_gemma":[0.0000954326,0.00008050746,0.00007670393,0.0002560823,0.00005709331,0.00006924064,0.00002790291,0.0002294107,0.00004939675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005686001,"about_ca_system_score_gemma":0.0004284703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008097786,"about_ca_topic_score_gemma":0.0003284369,"domain_scores_codex":[0.9991604,0.0000227138,0.0001847943,0.0002503588,0.0001477455,0.0002339767],"domain_scores_gemma":[0.9994356,0.0001757638,0.00002273759,0.0002168226,0.00005055549,0.00009853271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001070531,0.0001050619,0.06524841,0.00082534,0.0002753031,0.00190929,0.01753124,0.004068931,0.8000399,0.003432251,0.0915545,0.01393919],"study_design_scores_gemma":[0.000437617,0.0002931478,0.0054987,0.001127175,0.00004704196,0.00003284612,0.00215289,0.01956816,0.7008108,0.00005802749,0.2697774,0.0001961489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919412,0.002328406,0.00008160092,0.002059811,0.0008607749,0.000359781,0.00007493119,0.00005176364,0.002241787],"genre_scores_gemma":[0.9982972,0.00004485609,0.00005284983,0.0004492137,0.0003033354,0.0002365932,0.000009765876,0.00001845772,0.0005877892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1782229,"threshold_uncertainty_score":0.3282999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02419449456736194,"score_gpt":0.2860723792388792,"score_spread":0.2618778846715173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}