{"id":"W4390704973","doi":"10.7554/elife.89520.3.sa0","title":"eLife assessment: The Na+ leak channel NALCN controls spontaneous activity and mediates synaptic modulation by α2-adrenergic receptors in auditory neurons","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Neuroscience; Adrenergic; Receptor; Adrenergic receptor; Modulation (music); Leak; Chemistry; Biology; Internal medicine; Medicine; Physics; Acoustics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003111022,0.0006419717,0.0007688907,0.001459148,0.001755291,0.003530266,0.001685311,0.001793765,0.1002938],"category_scores_gemma":[0.01001823,0.0004755865,0.0004612781,0.0008416582,0.001340929,0.002367111,0.003425063,0.002086046,0.04848931],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002307229,"about_ca_system_score_gemma":0.00738217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00817462,"about_ca_topic_score_gemma":0.02878345,"domain_scores_codex":[0.9962843,0.0001706371,0.0001767276,0.0003692016,0.002450906,0.0005483227],"domain_scores_gemma":[0.9864672,0.0007777774,0.0009830664,0.0005842297,0.009322054,0.001865699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001187789,0.0001248201,0.006486851,0.001256919,0.0001129832,0.001505551,0.0005776657,0.0008645473,0.1141985,0.01630052,0.5935315,0.2638524],"study_design_scores_gemma":[0.0001755272,0.0001053454,0.0140973,0.0004031915,0.00007274273,0.0008638226,0.0007786399,0.002786651,0.08188282,0.007555619,0.891215,0.00006328773],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.1575992,0.01385473,0.1026682,0.1246648,0.04701281,0.001313241,0.02982282,0.01810675,0.5049574],"genre_scores_gemma":[0.2237039,0.00849398,0.04482028,0.006493794,0.004326764,0.0003773281,0.0192823,0.003236823,0.689265],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.1002938,"threshold_uncertainty_score":0.3355161,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04419551818058703,"score_gpt":0.3587496285923626,"score_spread":0.3145541104117756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}