{"id":"W4390705941","doi":"10.3390/curroncol31010024","title":"Adoption of Total Neoadjuvant Therapy in the Treatment of Locally Advanced Rectal Cancer","year":2024,"lang":"en","type":"review","venue":"Current Oncology","topic":"Colorectal Cancer Surgical Treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Colorectal cancer; Neoadjuvant therapy; Chemotherapy; Adjuvant; Oncology; Clinical trial; Standard of care; Internal medicine; Complete response; Surgery; Disease; Cancer; Breast cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005309522,0.0004532335,0.0008818659,0.002045868,0.000212987,0.0006580938,0.0005896579,0.000610491,0.00307656],"category_scores_gemma":[0.0010736,0.0001574603,0.0006821667,0.002098252,0.0003207392,0.0007357253,0.0003509859,0.001028114,0.0008059388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004664273,"about_ca_system_score_gemma":0.001037483,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001274311,"about_ca_topic_score_gemma":0.003407161,"domain_scores_codex":[0.9997794,0.00005298719,0.00004657993,0.00002979254,0.00007627856,0.00001499649],"domain_scores_gemma":[0.9995772,0.0002389123,0.00007886722,0.000008841698,0.00007643425,0.0000197038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006356872,0.00003386738,0.0002261591,0.05057673,0.0001489523,0.0001256636,0.00006556647,0.000221785,0.0006173585,0.001795373,0.02344855,0.9226766],"study_design_scores_gemma":[0.00002838515,0.0001351785,0.002282051,0.02676344,0.0004371883,0.001741494,0.0001055381,0.00009113313,0.0003289507,0.001208085,0.966858,0.00002059286],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008427372,0.9990875,0.00003482223,0.000147536,0.0001045043,0.000003729354,0.00001261969,0.000002868263,0.0005221951],"genre_scores_gemma":[0.0004931504,0.9991084,0.00006844567,0.0001212422,0.00004864052,0.000003512734,0.00001642657,7.472113e-7,0.000139545],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00307656,"threshold_uncertainty_score":0.01029211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2243882212070887,"score_gpt":0.5079433430417725,"score_spread":0.2835551218346838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}