{"id":"W4390706040","doi":"10.1038/s41416-023-02560-z","title":"Autoantibodies, antigen-autoantibody complexes and antigens complement CA125 for early detection of ovarian cancer","year":2024,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sinai Health System","funders":"University of Texas MD Anderson Cancer Center; Cancer Prevention and Research Institute of Texas; Minnesota Ovarian Cancer Alliance; Division of Cancer Prevention, National Cancer Institute; National Cancer Institute; U.S. Department of Health and Human Services","keywords":"Autoantibody; Ovarian cancer; Medicine; Biomarker; Antigen; Stage (stratigraphy); Osteopontin; Oncology; Cancer; Immunology; Internal medicine; Antibody; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019728,0.0004178151,0.0003935452,0.001045119,0.0001329027,0.0004113084,0.0002354622,0.0003195863,0.0005349462],"category_scores_gemma":[0.002843739,0.0001684697,0.0002549542,0.000379356,0.00017481,0.0002450543,0.0002464087,0.0003414923,0.00007537359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00039331,"about_ca_system_score_gemma":0.000305115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009708719,"about_ca_topic_score_gemma":0.001930293,"domain_scores_codex":[0.9993501,0.0002638328,0.00004819874,0.00009541059,0.0001943017,0.00004811832],"domain_scores_gemma":[0.9988806,0.0005353869,0.0002546173,0.00004419896,0.000160169,0.0001250525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0112399,0.0005451473,0.7080492,0.0003393169,0.0007597747,0.0001329003,0.00007515697,0.001865515,0.1089254,0.00008022903,0.0005891553,0.1673982],"study_design_scores_gemma":[0.000766213,0.01687707,0.8711216,0.0001399105,0.0009402143,0.001745596,0.0001110987,0.01879567,0.08641524,0.0004378305,0.002596194,0.00005340691],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923527,0.005831648,0.001157405,0.000121856,0.000023415,0.00004258435,0.00007202422,0.00002647986,0.0003719479],"genre_scores_gemma":[0.9968342,0.0004035022,0.0024799,0.00004415189,0.00001431216,0.00001335619,0.00008551071,0.000001530646,0.0001235878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0019728,"threshold_uncertainty_score":0.01043326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02331385625616697,"score_gpt":0.3370818268723073,"score_spread":0.3137679706161404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}