{"id":"W4390707083","doi":"10.1096/fj.202301428rr","title":"<scp>CD4</scp> <sup>+</sup> T cell‐derived <scp>IFN</scp> ‐γ and <scp>LIGHT</scp> synergistically upregulate chemokine production from airway smooth muscle cells","year":2024,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Cell biology; Chemokine; Downregulation and upregulation; Lymphotoxin; CCL5; CXCL14; CXCL16; T cell; Chemistry; CXCL2; CXCL9; Biology; Molecular biology; CXCL10; Immunology; Chemokine receptor; Inflammation; IL-2 receptor; Cytokine; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001523937,0.0004916122,0.0002637958,0.0002675578,0.0001403565,0.0003636696,0.0001510451,0.0003576292,0.004632331],"category_scores_gemma":[0.00009665071,0.0001573123,0.0003090942,0.0001445662,0.0002445572,0.000147802,0.0001811476,0.0009431689,0.001119755],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002414245,"about_ca_system_score_gemma":0.0002109482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005800411,"about_ca_topic_score_gemma":0.0008990472,"domain_scores_codex":[0.9997119,0.00005699354,0.00002417089,0.00003547689,0.00007831919,0.00009305425],"domain_scores_gemma":[0.9998486,0.00003324601,0.00003016076,0.00002118936,0.00001763881,0.00004918257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001611898,0.0000397763,0.0001395093,0.00002269372,0.00000341294,0.00004044601,0.000004782572,0.00005263953,0.9989992,0.00002479837,0.0000795974,0.00043185],"study_design_scores_gemma":[0.00004175565,0.0006419533,0.006551624,0.000008643134,0.00001589833,0.0002685817,0.00004468062,0.0008225932,0.9896131,0.00003879673,0.001948622,0.000003727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939656,0.0005642906,0.001512673,0.0001911582,0.00005679437,0.00005442535,0.0009303379,0.0001102464,0.002614551],"genre_scores_gemma":[0.9896356,0.0003348347,0.002094512,0.0002035012,0.00005268028,0.0001298079,0.001482109,0.00004502148,0.00602184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004632331,"threshold_uncertainty_score":0.01549667,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009239963448074429,"score_gpt":0.2222082539511992,"score_spread":0.2129682905031248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}