{"id":"W4390715266","doi":"10.19080/gjpps.2021.08.555733.","title":"Quantitative Estimation of Avicel Polymer and its Impact on Spray Pattern, Plume Geometry and Droplet Size in Nasal Spray Products","year":2021,"lang":"en","type":"article","venue":"Global Journal of Pharmacy & Pharmaceutical Sciences","topic":"Analytical Methods in Pharmaceuticals","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chromatography; Microcrystalline cellulose; Dosage form; Nasal spray; Polymer; Spray drying; Ethyl cellulose; Chemistry; Materials science; Process engineering; Cellulose; Organic chemistry; Pharmacology; Medicine; Nasal administration","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002147916,0.0003745464,0.0007079116,0.0001511383,0.0001237001,0.000126563,0.0004519662,0.00009514588,0.001231912],"category_scores_gemma":[0.003549606,0.0002859298,0.0001454182,0.001514027,0.0008507888,0.0006580985,0.000237822,0.0007673705,0.000009706206],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001898321,"about_ca_system_score_gemma":0.0004842398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002242263,"about_ca_topic_score_gemma":0.000001528985,"domain_scores_codex":[0.9960245,0.000439207,0.001084033,0.0005835517,0.001196982,0.0006716533],"domain_scores_gemma":[0.9963433,0.001893501,0.0005068564,0.0001421791,0.0004572667,0.0006569674],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00190263,0.001180612,0.08156222,0.0006996379,0.0003659912,0.0006730978,0.0002549928,0.0007798732,0.8172266,0.002224152,0.0001946857,0.09293546],"study_design_scores_gemma":[0.003538186,0.0002942456,0.00597638,0.0003530577,0.0003272569,0.0007604972,0.0002869309,0.03367266,0.953142,0.0007946476,0.0004383533,0.0004158183],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859815,0.009234759,0.0002966956,0.002937187,0.0002585267,0.0001126719,0.00009779386,0.00001464706,0.001066258],"genre_scores_gemma":[0.9943574,0.0008878026,0.003871517,0.0006858837,0.0001552622,0.000002362412,0.00000140175,0.00001418301,0.00002417615],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1359153,"threshold_uncertainty_score":0.9999593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06981705013415795,"score_gpt":0.467334446809892,"score_spread":0.397517396675734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}