{"id":"W4390725672","doi":"10.1186/s40035-023-00395-5","title":"Death-associated protein kinase 1 as a therapeutic target for Alzheimer's disease","year":2024,"lang":"en","type":"article","venue":"Translational Neurodegeneration","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"Natural Science Foundation of Fujian Province; National Natural Science Foundation of China","keywords":"Neurology; Disease; Medicine; Neuroscience; Alzheimer's disease; Psychology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001211948,0.0001944612,0.0001565019,0.0001333362,0.0001772145,0.00009087456,0.00004801836,0.00006123661,0.0002304135],"category_scores_gemma":[0.00003838219,0.000168591,0.0002064686,0.0002017173,0.00003330849,0.0002113181,0.000004839468,0.0001142805,0.0001129913],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003834528,"about_ca_system_score_gemma":0.0006412048,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001109105,"about_ca_topic_score_gemma":0.000003378153,"domain_scores_codex":[0.9985157,0.00007979364,0.0002274828,0.0004149612,0.0004876838,0.0002743496],"domain_scores_gemma":[0.9992549,0.00008252541,0.0000260374,0.000159307,0.0001558494,0.0003213725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.03049984,0.0159825,0.0907789,0.002470179,0.07268845,0.004224781,0.001969671,0.007559313,0.147338,0.5145884,0.007698288,0.1042017],"study_design_scores_gemma":[0.01402664,0.003991066,0.2392719,0.00068869,0.009499287,0.00006025332,0.00001448173,0.5283741,0.08476524,0.1019289,0.01591316,0.001466265],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9319459,0.03726433,0.007710451,0.01489527,0.0002802841,0.005644382,0.0009443992,0.0005445733,0.0007703759],"genre_scores_gemma":[0.9949957,0.00003161209,0.0007034469,0.0003045666,0.0002439511,0.0007018555,0.002730333,0.00005574085,0.0002327655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5208148,"threshold_uncertainty_score":0.687494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05358277401492418,"score_gpt":0.3357667615703891,"score_spread":0.2821839875554649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}