{"id":"W4390740624","doi":"10.1177/09636897231221882","title":"Safety and Tolerability of Intra-Articular Injection of Adipose-Derived Mesenchymal Stem Cells GXCPC1 in 11 Subjects With Knee Osteoarthritis: A Nonrandomized Pilot Study Without a Control Arm","year":2024,"lang":"en","type":"article","venue":"Cell Transplantation","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Osteoarthritis; WOMAC; Adverse effect; Tolerability; Clinical endpoint; Placebo; Knee pain; Physical therapy; Clinical trial; Surgery; Internal medicine; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004041643,0.0002238285,0.0007282928,0.0001978723,0.00003455425,0.00001769311,0.00003020901,0.00006625954,0.00002189842],"category_scores_gemma":[0.000004887032,0.0001826722,0.00006526515,0.0002466902,0.00008402302,0.0001578254,0.000003804746,0.0001408546,0.000001999748],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004816282,"about_ca_system_score_gemma":0.0001087535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002326686,"about_ca_topic_score_gemma":0.002216545,"domain_scores_codex":[0.9982911,0.0002456254,0.0006050787,0.0003749361,0.0002823807,0.0002008632],"domain_scores_gemma":[0.9993568,0.0001854475,0.0001112227,0.0001666225,0.00009160636,0.00008830221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.07813139,0.00276696,0.04800806,0.002066332,0.0001918376,0.0004316252,0.01367274,0.0001723054,0.8451548,0.00003258055,2.853712e-7,0.009371051],"study_design_scores_gemma":[0.1694101,0.07453224,0.02060906,0.00185928,0.002221945,0.0002393527,0.003232628,0.0005921818,0.7269647,0.00003118391,0.000003163175,0.0003042254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936497,0.0008535096,0.0017015,0.00001958945,0.0001295374,0.003406314,0.00005756726,0.00005642907,0.0001258348],"genre_scores_gemma":[0.999306,0.0001129346,0.0003024051,0.00001028776,0.00001840336,0.0001302442,0.00003747477,0.00002812772,0.00005415797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1181902,"threshold_uncertainty_score":0.7449157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008766362608214767,"score_gpt":0.2214887187448384,"score_spread":0.2127223561366236,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}