{"id":"W4390740644","doi":"10.1101/2024.01.08.574619","title":"DNA methylation enables recurrent endogenization of giant viruses in an animal relative","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Japan Society for the Promotion of Science; Queen Mary University of London; Horizon 2020 Framework Programme; Ministerio de Ciencia e Innovación; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Transposable element; Biology; Genome; DNA methylation; Giant Virus; Gene; Genetics; Methylation; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001167344,0.0002044235,0.0001464102,0.0001511731,0.0001083704,0.0002334806,0.0001447476,0.0003734608,0.0008942419],"category_scores_gemma":[0.0001770621,0.0001297509,0.0001701749,0.00008156442,0.0002263759,0.0001223299,0.0004005918,0.0003387212,0.0002903944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001759731,"about_ca_system_score_gemma":0.00009818962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004539819,"about_ca_topic_score_gemma":0.0006142901,"domain_scores_codex":[0.9998975,0.00001817915,0.000004970529,0.00003082773,0.0000237862,0.0000247026],"domain_scores_gemma":[0.9998561,0.00004005304,0.00004329452,0.00002604934,0.00001003657,0.00002450191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000010193,0.000001300358,0.000132317,0.000004280317,0.000001006862,0.00001381649,0.000006433383,0.000009544872,0.9995309,0.00005020638,0.000002983211,0.0002369471],"study_design_scores_gemma":[0.000003613226,0.0001245842,0.009096601,0.000004620294,0.000009672391,0.0003731714,0.00004199849,0.0009484998,0.9868343,0.0001260437,0.002432411,0.000004372579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957378,0.0003254111,0.003055648,0.00003688677,0.000008717385,0.00000758887,0.00006829306,0.0000356696,0.0007239566],"genre_scores_gemma":[0.9964229,0.0001285567,0.001785622,0.00002136666,0.000003659813,0.0000053425,0.0001562673,0.00002246192,0.001453778],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008942419,"threshold_uncertainty_score":0.002991557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02172499198496006,"score_gpt":0.2504069187883922,"score_spread":0.2286819268034322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}