{"id":"W4390750655","doi":"10.3390/ijms25020814","title":"Molecular Mechanisms of Reelin in the Enteric Nervous System and the Microbiota–Gut–Brain Axis: Implications for Depression and Antidepressant Therapy","year":2024,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Diet and metabolism studies","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"","keywords":"Gut–brain axis; Antidepressant; Enteric nervous system; Reelin; Depression (economics); Gut flora; Neuroscience; Central nervous system; Medicine; Biology; Bioinformatics; Immunology; Internal medicine; Hippocampus; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002801295,0.0005012521,0.0006439452,0.000460867,0.0001861725,0.0007980498,0.0004031949,0.0006829639,0.001448213],"category_scores_gemma":[0.0002049264,0.0001480128,0.0005195787,0.0002699472,0.0003398944,0.0005887785,0.000418965,0.0009495228,0.0003927308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004159895,"about_ca_system_score_gemma":0.0003451519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006152499,"about_ca_topic_score_gemma":0.00124749,"domain_scores_codex":[0.9998853,0.00003150355,0.00001434092,0.00002155387,0.00002100656,0.00002628538],"domain_scores_gemma":[0.9999248,0.00001282758,0.00002588732,0.000004342364,0.00001763486,0.00001451604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.002777946,0.000579824,0.007716719,0.01057503,0.001084205,0.004890003,0.0008509416,0.00131374,0.332864,0.03419989,0.01481435,0.5883333],"study_design_scores_gemma":[0.000822037,0.006113608,0.1830586,0.005615001,0.002407818,0.01673603,0.002724804,0.004601056,0.1151191,0.0499567,0.6125771,0.0002681942],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05793551,0.9258482,0.003647689,0.004730077,0.0006001593,0.00005857818,0.0002371105,0.00006519798,0.006877495],"genre_scores_gemma":[0.2147323,0.7701337,0.004149851,0.001596338,0.0006326449,0.000114066,0.0002918099,0.00001756626,0.008331682],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001448213,"threshold_uncertainty_score":0.004844785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01627098089112201,"score_gpt":0.3122160511620569,"score_spread":0.2959450702709349,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}