{"id":"W4390789584","doi":"10.1101/2024.01.11.575259","title":"SAX-7/L1CAM acts with the adherens junction proteins MAGI-1, HMR-1/Cadherin, and AFD-1/Afadin to promote glial-mediated dendrite extension","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"National Institutes of Health","keywords":"Adherens junction; PDZ domain; Cell biology; Cadherin; Biology; Scaffold protein; Tight junction; Dendrite (mathematics); Cytoskeleton; Cytoplasm; Catenin; Nectin; Signal transducing adaptor protein; Cell adhesion; Anatomy; Cell; Signal transduction; Wnt signaling pathway; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009871639,0.000349343,0.0001464545,0.0001692106,0.0002460102,0.0002833939,0.0001923634,0.0002616295,0.001670897],"category_scores_gemma":[0.00006533965,0.0001902718,0.0003413141,0.00006495813,0.0001797066,0.000183108,0.0003363384,0.0006823624,0.0006863035],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000381059,"about_ca_system_score_gemma":0.0001759562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005570535,"about_ca_topic_score_gemma":0.001488256,"domain_scores_codex":[0.9998692,0.00001360025,0.00001006422,0.00002490172,0.00004711908,0.00003521857],"domain_scores_gemma":[0.9998816,0.00001239023,0.00002234501,0.00001249016,0.00001082782,0.00006036164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001412329,0.000007206178,0.0001226084,0.000008180315,0.000001984345,0.00001391315,0.000002613633,0.00001477257,0.9996334,0.00002869025,0.00001203077,0.0001403577],"study_design_scores_gemma":[0.000005674507,0.00007321027,0.006163927,0.000003853308,0.000007024383,0.0001161946,0.00002256389,0.0009978384,0.9917318,0.00001448727,0.000861707,0.000001693493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965932,0.0004300942,0.001389977,0.00006109825,0.00001327875,0.00001078032,0.0001075857,0.00004687037,0.001347071],"genre_scores_gemma":[0.9946596,0.0001678897,0.001447615,0.00005183654,0.000003489215,0.00001292069,0.0002678526,0.00001185945,0.003376917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001670897,"threshold_uncertainty_score":0.005589724,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008555242000663666,"score_gpt":0.2044483863941628,"score_spread":0.1958931443934992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}