{"id":"W4390819889","doi":"10.1021/acs.bioconjchem.3c00522","title":"Palladium-Mediated <i>S</i>-Arylation of Cysteine Residues with 4-[<sup>18</sup>F]Fluoroiodobenzene ([<sup>18</sup>F]FIB)","year":2024,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; LNCaP; Bioconjugation; Peptidomimetic; Radioligand; Cysteine; Combinatorial chemistry; Prostate cancer; Biochemistry; Peptide; Cancer; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000192312,0.0008421949,0.0002851012,0.0002026055,0.0001783584,0.0002286981,0.0004267773,0.0003241672,0.0007159502],"category_scores_gemma":[0.0002398357,0.0002143814,0.0003105744,0.0002143849,0.0003200129,0.000219758,0.0002499467,0.0003653308,0.0004242504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003306693,"about_ca_system_score_gemma":0.0002752843,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008190185,"about_ca_topic_score_gemma":0.00111946,"domain_scores_codex":[0.9998584,0.00001930506,0.00001168566,0.00005009406,0.00003112066,0.00002939247],"domain_scores_gemma":[0.9998884,0.0000205076,0.000040688,0.00001320431,0.00002509483,0.00001207607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003041382,0.000006505938,0.0001075481,0.00005551569,0.000007546054,0.00006156371,0.00001454637,0.00007570841,0.9970304,0.0001175365,0.00006570939,0.002427017],"study_design_scores_gemma":[0.000002997403,0.0000972887,0.000355554,0.000001294417,0.000006976432,0.0002167336,0.000004075826,0.0001790789,0.9975137,0.00001890001,0.00159976,0.000003630702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.892036,0.0044934,0.09370267,0.0002446567,0.00009888883,0.0001864425,0.0004769092,0.0009223454,0.007838676],"genre_scores_gemma":[0.9507946,0.002907535,0.04120776,0.0001416353,0.00002403765,0.00008763172,0.0006086652,0.00007639819,0.004151777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008421949,"threshold_uncertainty_score":0.002399206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01627803911795779,"score_gpt":0.2438493304065425,"score_spread":0.2275712912885847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}