{"id":"W4390824361","doi":"10.1002/pld3.563","title":"Creating saponin‐free yellow pea seeds by <i>CRISPR/Cas9</i>‐enabled mutagenesis on β‐amyrin synthase","year":2024,"lang":"en","type":"article","venue":"Plant Direct","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Research Council (Canada); Global Institute for Water Security; University of Saskatchewan; University of Calgary","funders":"National Research Council Canada; Natural Sciences and Engineering Research Council of Canada; RES’EAU-WaterNET; Alberta Innovates","keywords":"CRISPR; Mutagenesis; Cas9; Biology; Saponin; ATP synthase; Genetics; Computational biology; Mutation; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002194292,0.0002838157,0.0002198335,0.00008224099,0.0000970744,0.00009373331,0.0002416203,0.0001507738,0.00006710851],"category_scores_gemma":[0.0001410354,0.0002648464,0.0001376724,0.0001423894,0.00002902593,0.000004206022,0.0001031952,0.0001372771,0.0000552147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002472438,"about_ca_system_score_gemma":0.00004290322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007863151,"about_ca_topic_score_gemma":0.00003229328,"domain_scores_codex":[0.998603,0.00004519181,0.0002181918,0.0005424246,0.0001866695,0.0004045043],"domain_scores_gemma":[0.9992577,0.00009162803,0.00002825312,0.000467015,0.00002124805,0.0001341713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007298469,0.00005744633,0.00019748,0.0001299114,0.0001565407,0.0001210448,0.000101049,0.0007733762,0.9072463,0.00002460809,0.0878848,0.003234454],"study_design_scores_gemma":[0.000255519,0.0001650194,0.0001020097,0.0001245968,0.00005941127,0.00005406344,0.00004789342,0.001893625,0.8027065,0.000006854289,0.1942407,0.0003438215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9185469,0.01685022,0.004253386,0.0002996014,0.001254867,0.0004194458,0.00145305,0.0003782548,0.05654424],"genre_scores_gemma":[0.9913844,0.0007250105,0.000411247,0.0001571857,0.0004497529,0.00004486606,0.00050602,0.00007305604,0.006248411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1063559,"threshold_uncertainty_score":0.9999804,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005736655756264831,"score_gpt":0.2565798649874899,"score_spread":0.2508432092312251,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}