{"id":"W4390863149","doi":"10.1101/2024.01.14.575580","title":"The <i>Streptococcus</i> phage protein paratox is an intrinsically disordered protein","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biophysics; Chemistry; Circular dichroism; Bacteriophage; Protein folding; Globular protein; Molten globule; Crystallography; Folding (DSP implementation); Magnetic tweezers; Kinetics; Intrinsically disordered proteins; DNA; Biochemistry; Biology; Physics; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008509109,0.0002710639,0.0001775028,0.000104087,0.0001405226,0.0002297451,0.0001459558,0.0001748735,0.0007011166],"category_scores_gemma":[0.0001571556,0.00006650747,0.0001440279,0.0001134867,0.0001711818,0.0001343018,0.0001396261,0.000281522,0.0002953536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002576227,"about_ca_system_score_gemma":0.0001502795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000528821,"about_ca_topic_score_gemma":0.0004232438,"domain_scores_codex":[0.9999126,0.00001542815,0.000006172339,0.00002456821,0.00002806398,0.00001318902],"domain_scores_gemma":[0.9999126,0.0000160261,0.00003262005,0.000008447706,0.00001249677,0.00001770838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003457158,0.000007419909,0.0003991172,0.000015636,0.000002600982,0.00002917194,0.000005759809,0.00008395571,0.9989281,0.00004932754,0.00002236296,0.0004219502],"study_design_scores_gemma":[0.000005048013,0.0001705662,0.005891088,0.000004773121,0.00000809168,0.000368337,0.00002370949,0.001766132,0.9901064,0.00005138612,0.001599874,0.000004526615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960777,0.0004030273,0.002621417,0.00006324266,0.00001154569,0.000009940785,0.0002106937,0.00005448885,0.0005479947],"genre_scores_gemma":[0.9951143,0.0001880426,0.002710811,0.00003878722,0.000005910964,0.00001076379,0.0006630616,0.00002077562,0.001247497],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007011166,"threshold_uncertainty_score":0.002345502,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00922340975991341,"score_gpt":0.2186909904907116,"score_spread":0.2094675807307982,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}