{"id":"W4390901666","doi":"10.1016/j.toxicon.2024.107492","title":"Treatment of Moderate-to-Severe Glabellar Lines With RelabotulinumtoxinA, an Investigational Liquid Botulinum Toxin: Clinical Efficacy and Safety Results From the READY-1 Phase 3 Trial","year":2024,"lang":"en","type":"article","venue":"Toxicon","topic":"Botulinum Toxin and Related Neurological Disorders","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Botulinum toxin; Investigational Drugs; Clinical trial; Medicine; Psychology; Internal medicine; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008156138,0.0009484374,0.001419071,0.0002565577,0.0003805447,0.0005901296,0.0005481471,0.0008333283,0.003163892],"category_scores_gemma":[0.0005392768,0.0001993421,0.001726339,0.0002585482,0.00045595,0.0005321413,0.0002036041,0.001993405,0.0005325447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007099504,"about_ca_system_score_gemma":0.0006470861,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001524697,"about_ca_topic_score_gemma":0.0049525,"domain_scores_codex":[0.9998049,0.00006767269,0.000009654304,0.00003164694,0.00002893617,0.00005717812],"domain_scores_gemma":[0.9996855,0.0000844547,0.00007062938,0.00002186809,0.00002410666,0.0001134723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4767009,0.02327305,0.005024955,0.002869961,0.003520151,0.0004294138,0.0002460333,0.001466611,0.04624165,0.0006598436,0.0109537,0.4286139],"study_design_scores_gemma":[0.6112006,0.3355571,0.03221187,0.0003521055,0.001218261,0.001510076,0.0001941828,0.00233051,0.006188875,0.0008790646,0.008276414,0.00008082641],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819869,0.01104836,0.0008854635,0.0006744103,0.0002143562,0.0005733083,0.0007004169,0.0002026952,0.003714119],"genre_scores_gemma":[0.9864698,0.005560196,0.001364211,0.001549647,0.000130306,0.0004045886,0.001360117,0.0000418943,0.003119246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003163892,"threshold_uncertainty_score":0.01058429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06874475267176762,"score_gpt":0.3576863047558917,"score_spread":0.2889415520841241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}