{"id":"W4390903581","doi":"10.21203/rs.3.rs-3809489/v1","title":"Checkpoint inhibitor immunotherapy induced inflammatory arthritis secondary to Nivolumab and Ipilimumab: a pediatric first","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Ipilimumab; Nivolumab; Internal medicine; Arthritis; Inflammatory arthritis; Rheumatology; Surgery; Cancer; Dermatology; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005027693,0.0009829135,0.0008311215,0.0004765168,0.000634143,0.001021347,0.0004438455,0.001699719,0.0039207],"category_scores_gemma":[0.001238278,0.0003005026,0.0009356234,0.0003356849,0.0005471511,0.000603481,0.0005473893,0.002264408,0.001103513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008109953,"about_ca_system_score_gemma":0.0009725064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001146177,"about_ca_topic_score_gemma":0.001039907,"domain_scores_codex":[0.9996258,0.00009363231,0.00003676702,0.00007007649,0.00007680653,0.00009672897],"domain_scores_gemma":[0.9989616,0.0003082128,0.0002733079,0.0001221439,0.00008879373,0.0002459743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.003107015,0.001411712,0.04215431,0.0008471889,0.0004452649,0.8062651,0.0004560187,0.0006993493,0.01849825,0.009514371,0.02775761,0.08884385],"study_design_scores_gemma":[0.0006805265,0.002120251,0.05021599,0.0003620943,0.0005201417,0.8809648,0.000330866,0.002313597,0.0143714,0.002733116,0.04534082,0.00004652196],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8656712,0.03022728,0.0169205,0.02266503,0.003160048,0.0005053972,0.002065282,0.0008823044,0.05790292],"genre_scores_gemma":[0.9618459,0.01075989,0.006258438,0.00400973,0.003067742,0.00008564906,0.0009126912,0.000164116,0.01289585],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0039207,"threshold_uncertainty_score":0.01311606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03186515174350881,"score_gpt":0.3453370719268126,"score_spread":0.3134719201833038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}