{"id":"W4390913319","doi":"10.1161/hypertensionaha.123.22334","title":"Genome-Wide Interaction Analysis With DASH Diet Score Identified Novel Loci for Systolic Blood Pressure","year":2024,"lang":"en","type":"article","venue":"Hypertension","topic":"Nutritional Studies and Diet","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke; School of Public Health, University of Texas Health Science Center at Houston; National Heart, Lung, and Blood Institute; National University of Singapore; Wageningen University and Research; Edith Cowan University; National Health and Medical Research Council; Johns Hopkins Bloomberg School of Public Health; Queen Mary University of London; University of North Carolina at Chapel Hill; Canadian Institutes of Health Research; University of Washington; Curtin University of Technology; University of California, Los Angeles; National Cancer Institute; National Institute on Aging; Menzies Institute for Medical Research; National University Health System; Milken Institute School of Public Health, George Washington University; Universität Regensburg; National Institutes of Health; University of Notre Dame Australia; U.S. Department of Health and Human Services; Murdoch University; Medical Research Council; University of Tasmania; Genome Institute of Singapore; Leids Universitair Medisch Centrum; National Medical Research Council; Universiteit Leiden; Government of Western Australia; Agency for Science, Technology and Research; Hunter Medical Research Institute; Women and Infants Research Foundation; Australian Government; University of Notre Dame; University of Texas Health Science Center at Houston; Biomedical Research Council; Raine Medical Research Foundation; College of Engineering, Michigan State University; Johns Hopkins University; National Institute for Health and Care Research; College of Human Medicine, Michigan State University; Michigan State University; Department of Health, Government of Western Australia; George Washington University; Safe Work Australia; University of Southern California","keywords":"Dash; Quantitative trait locus; Expression quantitative trait loci; Single-nucleotide polymorphism; Biology; Population; Locus (genetics); Genetics; Genome-wide association study; Blood pressure; Heritability; Genotype; Genetic association; Minor allele frequency; Genetic epidemiology; Internal medicine; Endocrinology; Gene; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00274651,0.001291604,0.001673038,0.001570181,0.0006146489,0.001255545,0.0009877712,0.001110272,0.005183891],"category_scores_gemma":[0.004912526,0.0006062346,0.006406661,0.002423057,0.0005141358,0.0004103827,0.00109415,0.001462606,0.0003338747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003599769,"about_ca_system_score_gemma":0.0006120927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005939135,"about_ca_topic_score_gemma":0.008512683,"domain_scores_codex":[0.9963408,0.00125133,0.000330469,0.001368803,0.0003720701,0.0003364318],"domain_scores_gemma":[0.9942707,0.004020606,0.0006844677,0.0004881646,0.0002381235,0.0002979558],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.009040074,0.0002171146,0.8778946,0.0007418444,0.06382012,0.001978233,0.0002912247,0.001817969,0.01979633,0.0005084943,0.001549399,0.02234454],"study_design_scores_gemma":[0.0005486492,0.0007109005,0.955155,0.00007699855,0.03169059,0.001059945,0.0001315086,0.005610561,0.002306744,0.0009761077,0.001673695,0.00005925434],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791721,0.007576277,0.007795669,0.0005551308,0.000177091,0.00003147028,0.003353792,0.0002770815,0.001061465],"genre_scores_gemma":[0.9961499,0.0005005276,0.00171988,0.0001729324,0.0000602929,0.00004155973,0.000858316,0.00004516272,0.00045141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005939135,"threshold_uncertainty_score":0.01734191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0375065732739388,"score_gpt":0.2699174779303213,"score_spread":0.2324109046563825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}