{"id":"W4390913319","doi":"10.1161/hypertensionaha.123.22334","title":"Genome-Wide Interaction Analysis With DASH Diet Score Identified Novel Loci for Systolic Blood Pressure","year":2024,"lang":"en","type":"article","venue":"Hypertension","topic":"Nutritional Studies and Diet","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke; School of Public Health, University of Texas Health Science Center at Houston; National Heart, Lung, and Blood Institute; National University of Singapore; Wageningen University and Research; Edith Cowan University; National Health and Medical Research Council; Johns Hopkins Bloomberg School of Public Health; Queen Mary University of London; University of North Carolina at Chapel Hill; Canadian Institutes of Health Research; University of Washington; Curtin University of Technology; University of California, Los Angeles; National Cancer Institute; National Institute on Aging; Menzies Institute for Medical Research; National University Health System; Milken Institute School of Public Health, George Washington University; Universität Regensburg; National Institutes of Health; University of Notre Dame Australia; U.S. Department of Health and Human Services; Murdoch University; Medical Research Council; University of Tasmania; Genome Institute of Singapore; Leids Universitair Medisch Centrum; National Medical Research Council; Universiteit Leiden; Government of Western Australia; Agency for Science, Technology and Research; Hunter Medical Research Institute; Women and Infants Research Foundation; Australian Government; University of Notre Dame; University of Texas Health Science Center at Houston; Biomedical Research Council; Raine Medical Research Foundation; College of Engineering, Michigan State University; Johns Hopkins University; National Institute for Health and Care Research; College of Human Medicine, Michigan State University; Michigan State University; Department of Health, Government of Western Australia; George Washington University; Safe Work Australia; University of Southern California","keywords":"Dash; Quantitative trait locus; Expression quantitative trait loci; Single-nucleotide polymorphism; Biology; Population; Locus (genetics); Genetics; Genome-wide association study; Blood pressure; Heritability; Genotype; Genetic association; Minor allele frequency; Genetic epidemiology; Internal medicine; Endocrinology; Gene; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009001933,0.0001494583,0.0003772444,0.0001924268,0.0001354398,0.00005280352,0.00004239038,0.00006782891,0.0000383591],"category_scores_gemma":[0.00008151611,0.0001035049,0.0002172297,0.0004503324,0.000033151,0.00009242818,0.00003738167,0.0001170304,0.00001786946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002292503,"about_ca_system_score_gemma":0.00003140705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008320571,"about_ca_topic_score_gemma":0.00006187773,"domain_scores_codex":[0.9989872,0.000008394548,0.0001970121,0.0003743283,0.0002447533,0.0001883032],"domain_scores_gemma":[0.9992743,0.0001183472,0.00004243969,0.0002045843,0.0002577555,0.0001025565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01982808,0.00706474,0.09519661,0.01608849,0.09509218,0.002022303,0.001279417,0.002865566,0.4989445,0.002397235,0.256807,0.00241391],"study_design_scores_gemma":[0.008935311,0.003679936,0.3878104,0.002660921,0.09147783,0.0009776592,0.001161013,0.02462957,0.004062961,0.0002437956,0.4734114,0.0009492228],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9773145,0.01249101,0.004237505,0.00363758,0.0003859742,0.0009373648,0.0001359719,0.000209603,0.0006504831],"genre_scores_gemma":[0.9965554,0.0002436078,0.0006272072,0.0006374978,0.0003046192,0.00007413048,0.0004981793,0.00002782094,0.001031509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4948815,"threshold_uncertainty_score":0.4220809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0375065732739388,"score_gpt":0.2699174779303213,"score_spread":0.2324109046563825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). 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