{"id":"W4390913401","doi":"10.1101/2024.01.15.575738","title":"Senolytic Treatment for Low Back Pain","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Fibromyalgia and Chronic Fatigue Syndrome Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Shriners Hospitals for Children - Canada; McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Arthritis Society; Réseau de Recherche en Santé Buccodentaire et Osseuse","keywords":"Medicine; Spinal cord; Low back pain; Vanillin; Senescence; Internal medicine; Pharmacology; Pathology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003472594,0.0002861286,0.0004549636,0.0003278317,0.0002881621,0.0003835943,0.0001928909,0.0006719941,0.01401958],"category_scores_gemma":[0.0005422927,0.00007997063,0.0002955637,0.0001834098,0.0001279118,0.0002087204,0.0001712066,0.0006153458,0.003033249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001787215,"about_ca_system_score_gemma":0.0004020279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002408047,"about_ca_topic_score_gemma":0.0006100156,"domain_scores_codex":[0.9998825,0.00002671065,0.00001520131,0.000009047094,0.00005548998,0.00001093818],"domain_scores_gemma":[0.9998177,0.00004695543,0.00004465571,0.000009200614,0.00004548195,0.00003593872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.002850353,0.0004396403,0.001246728,0.005575486,0.0002098029,0.001163017,0.0001159722,0.0001934338,0.09211097,0.003729834,0.6717296,0.2206352],"study_design_scores_gemma":[0.001006068,0.001894304,0.009490475,0.0008391897,0.0003508744,0.003879835,0.0001268231,0.0007329836,0.09806602,0.002541135,0.8810177,0.00005457642],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1727074,0.3675784,0.0143141,0.211883,0.1266768,0.001050486,0.01934607,0.003302148,0.08314163],"genre_scores_gemma":[0.4783578,0.1750181,0.02112629,0.04851972,0.03083824,0.0007048413,0.01047562,0.0004412679,0.2345182],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01401958,"threshold_uncertainty_score":0.04690015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02741056129573654,"score_gpt":0.276503862857219,"score_spread":0.2490933015614825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}