{"id":"W4390929340","doi":"10.2147/copd.s438153","title":"Biological Anti-IL-5/IL-5R Therapeutics for Chronic Obstructive Pulmonary Disease (COPD) with Specific Treatable Traits: A Real-World Retrospective Analysis","year":2024,"lang":"en","type":"article","venue":"International Journal of COPD","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Medicine; COPD; Exacerbation; Asthma; Internal medicine; Bronchodilator; Eosinophil; Retrospective cohort study; Medical record","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001818663,0.000320612,0.0004700981,0.001866236,0.000473512,0.001016005,0.0004424447,0.000468818,0.001743526],"category_scores_gemma":[0.004352797,0.0003544722,0.0007903275,0.001896311,0.0005020043,0.0004789303,0.0005855584,0.000379756,0.0004865718],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004660937,"about_ca_system_score_gemma":0.0006775112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001453927,"about_ca_topic_score_gemma":0.001460086,"domain_scores_codex":[0.9975343,0.0006894331,0.0004870463,0.0005453654,0.0005359211,0.0002079182],"domain_scores_gemma":[0.9930272,0.00152167,0.003596975,0.0008483193,0.0006845645,0.0003213549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001124114,0.00002724215,0.9965964,0.00005027562,0.00009747726,0.000658066,0.00006642169,0.00002642926,0.0001615243,0.00003099595,0.0001191723,0.002053672],"study_design_scores_gemma":[0.0000435806,0.0006276124,0.9769244,0.0001241439,0.0005088802,0.01675827,0.0006987015,0.0005155636,0.000655136,0.00006474438,0.00305745,0.0000215616],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943773,0.003360922,0.000768128,0.00005817351,0.00001069847,0.00007494265,0.0006450404,0.000008586225,0.0006961415],"genre_scores_gemma":[0.9979624,0.0007692861,0.0003592095,0.00006750483,0.00002734779,0.0000321206,0.0006761407,0.00000625881,0.00009975901],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001866236,"threshold_uncertainty_score":0.009618104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03309131190436106,"score_gpt":0.3342064639187637,"score_spread":0.3011151520144026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}