{"id":"W4390937479","doi":"10.1021/acs.jproteome.3c00591","title":"The 2023 Report on the Proteome from the HUPO Human Proteome Project","year":2024,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institute on Aging; University of California, San Diego; Farmer Family Foundation; Knut och Alice Wallenbergs Stiftelse; Swiss Institute of Bioinformatics; U.S. National Library of Medicine; Cycle for Survival; Leidos; National Institutes of Health; Canada Research Chairs; Neuroendocrine Tumor Research Foundation; Division of Biological Infrastructure; National Institute of General Medical Sciences; Office of the Director; National Institute of Environmental Health Sciences; Memorial Sloan-Kettering Cancer Center; Canadian Institutes of Health Research; National Science Foundation","keywords":"Human proteome project; Proteome; Human Protein Atlas; Proteomics; Computational biology; Biology; Bioinformatics; Protein expression; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004306933,0.001474597,0.0005574716,0.002841137,0.0009378158,0.002968425,0.0008258531,0.001368361,0.02372066],"category_scores_gemma":[0.003981954,0.0004134725,0.000640966,0.003385596,0.0002386684,0.001433655,0.002213862,0.001342684,0.04374307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001483963,"about_ca_system_score_gemma":0.005280209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009739535,"about_ca_topic_score_gemma":0.006973873,"domain_scores_codex":[0.9980185,0.0002313102,0.0001284001,0.0001828243,0.001212975,0.0002260573],"domain_scores_gemma":[0.997141,0.0001918574,0.0002185154,0.0001781111,0.001724129,0.0005463727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002578107,0.00004948894,0.001637163,0.0005837334,0.00003246889,0.0002306293,0.00004349593,0.0001894272,0.003394599,0.00200668,0.9424549,0.04911971],"study_design_scores_gemma":[0.00002145303,0.00004203128,0.006459166,0.0001967146,0.00001727654,0.000129776,0.00004430235,0.0001820308,0.002635806,0.0008470812,0.9894044,0.00001986464],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"review","genre_scores_codex":[0.01745824,0.02760837,0.02088465,0.03217302,0.02310983,0.001409682,0.6602226,0.005313573,0.21182],"genre_scores_gemma":[0.01192189,0.01201164,0.02250267,0.005430989,0.001882629,0.0008951251,0.882144,0.001008353,0.06220268],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.02372066,"threshold_uncertainty_score":0.07935351,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1226252390148985,"score_gpt":0.4533816358879416,"score_spread":0.330756396873043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}