{"id":"W4390972669","doi":"10.1186/s13023-024-03019-x","title":"A position statement on the post gene-therapy rehabilitation of aromatic I-amino acid decarboxylase deficiency patients","year":2024,"lang":"en","type":"article","venue":"Orphanet Journal of Rare Diseases","topic":"Autism Spectrum Disorder Research","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Alberta","funders":"PTC Therapeutics","keywords":"Occupational therapy; Medicine; Intellectual disability; Rehabilitation; Empowerment; Genetic enhancement; Physical therapy; Psychiatry; Gene; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006679389,0.0008653026,0.0007879963,0.0006257613,0.003177556,0.00291451,0.002081973,0.02237269,0.01340604],"category_scores_gemma":[0.02194505,0.0004495177,0.001281214,0.0004107391,0.001528801,0.00196613,0.002619493,0.01350969,0.0118974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002401164,"about_ca_system_score_gemma":0.01236884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003764151,"about_ca_topic_score_gemma":0.009823644,"domain_scores_codex":[0.9954782,0.001260264,0.0007721778,0.0003195412,0.001287357,0.0008824658],"domain_scores_gemma":[0.9808102,0.005060805,0.001443745,0.0004151786,0.006667502,0.005602623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006679293,0.0001271144,0.0006884339,0.0002785554,0.000009768711,0.0007483084,0.0002132337,0.0001040569,0.0006690039,0.001849702,0.9419909,0.05325406],"study_design_scores_gemma":[0.00007133859,0.0002256248,0.002073052,0.001412585,0.00002269057,0.0007548508,0.0005256224,0.0001141087,0.0004549683,0.00205128,0.9922461,0.00004784612],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.002703148,0.006513067,0.001874204,0.8264355,0.1402575,0.0004361659,0.0005259326,0.000165749,0.02108879],"genre_scores_gemma":[0.02917125,0.02590471,0.01452139,0.6563001,0.1584619,0.002582449,0.001843123,0.0002814844,0.1109337],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.02237269,"threshold_uncertainty_score":0.04484767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0170866285749049,"score_gpt":0.2891465302638425,"score_spread":0.2720599016889376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}