{"id":"W4390975572","doi":"10.1177/19476035231221211","title":"Management and Amelioration of Knee Joint Osteoarthritis in Adults Using a Novel High-Functional Bovine Collagen Peptide as a Nutritional Therapy: A Double-Blind, Prospective, Multicentric, Randomized, Active and Placebo Controlled, Five-Arm, Clinical Study to Evaluate the Efficacy, Safety, and Tolerability","year":2024,"lang":"en","type":"article","venue":"Cartilage","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Osteoarthritis; WOMAC; N-terminal telopeptide; Medicine; Type II collagen; Tolerability; Placebo; Type I collagen; Internal medicine; Knee pain; Arthritis; Gastroenterology; Pathology; Adverse effect; Chemistry; Biochemistry; Osteocalcin; Enzyme","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001541938,0.0002752981,0.001046859,0.0002306587,0.0001369613,0.00008142943,0.00003571228,0.00008145515,0.00005143915],"category_scores_gemma":[0.0002600744,0.0001932662,0.0001360294,0.0003198081,0.0002198247,0.0001404075,0.0001138767,0.000167412,0.000005429955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001377899,"about_ca_system_score_gemma":0.0001216713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006452142,"about_ca_topic_score_gemma":0.0002097787,"domain_scores_codex":[0.9974974,0.0003521855,0.0008273246,0.0006479122,0.0004459277,0.0002292055],"domain_scores_gemma":[0.9984421,0.0008504695,0.0001156642,0.0002057376,0.0002296196,0.0001564208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9806775,0.002237016,0.002251236,0.0001278098,0.0003281763,0.0001555886,0.003076395,0.00003066862,0.00283056,0.0009330905,0.00001184191,0.007340095],"study_design_scores_gemma":[0.9673813,0.007536338,0.0172673,0.0008225925,0.0008151883,0.00009401071,0.00305141,0.001228182,0.001247914,0.0002937502,0.00005031371,0.0002117179],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9787824,0.001919418,0.0001119219,0.0004680533,0.0002072483,0.01819724,0.0000817328,0.00003325855,0.0001987818],"genre_scores_gemma":[0.9977756,0.0003518081,0.0005013619,0.0001002321,0.0001235941,0.0009235266,0.00003410582,0.00002467443,0.0001651313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01899322,"threshold_uncertainty_score":0.7881168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03431947125683931,"score_gpt":0.318773189322653,"score_spread":0.2844537180658137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}