{"id":"W4390975572","doi":"10.1177/19476035231221211","title":"Management and Amelioration of Knee Joint Osteoarthritis in Adults Using a Novel High-Functional Bovine Collagen Peptide as a Nutritional Therapy: A Double-Blind, Prospective, Multicentric, Randomized, Active and Placebo Controlled, Five-Arm, Clinical Study to Evaluate the Efficacy, Safety, and Tolerability","year":2024,"lang":"en","type":"article","venue":"Cartilage","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Osteoarthritis; WOMAC; N-terminal telopeptide; Medicine; Type II collagen; Tolerability; Placebo; Type I collagen; Internal medicine; Knee pain; Arthritis; Gastroenterology; Pathology; Adverse effect; Chemistry; Biochemistry; Osteocalcin; Enzyme","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001348613,0.0009065368,0.001596997,0.0004803405,0.000376572,0.0004194625,0.0006034114,0.0013496,0.001338174],"category_scores_gemma":[0.0006480743,0.0004638371,0.0008030923,0.0002977656,0.0008555436,0.00056358,0.0002947157,0.001019338,0.0001944815],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002319972,"about_ca_system_score_gemma":0.0005957456,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003744646,"about_ca_topic_score_gemma":0.0008332414,"domain_scores_codex":[0.9995049,0.0002063595,0.00006230736,0.00009011277,0.00007014564,0.00006608169],"domain_scores_gemma":[0.9996158,0.00007112117,0.00009404967,0.00003224189,0.00004335257,0.0001434631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7718394,0.09391934,0.002539882,0.001968328,0.0009416199,0.0001677533,0.0001593115,0.0003400868,0.08134686,0.0001112235,0.0003792928,0.04628697],"study_design_scores_gemma":[0.2612045,0.7265444,0.006179203,0.00004054718,0.0003899185,0.00009638024,0.00003893323,0.0002925361,0.004547656,0.00003838626,0.0006105835,0.00001691835],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947672,0.00280339,0.0005534656,0.0001099837,0.0001472948,0.001198459,0.0001194546,0.00002427731,0.0002764098],"genre_scores_gemma":[0.9902597,0.002773271,0.002614027,0.0005696686,0.0003661287,0.001897185,0.0003441555,0.000007408158,0.001168464],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001596997,"threshold_uncertainty_score":0.007132232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03431947125683931,"score_gpt":0.318773189322653,"score_spread":0.2844537180658137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}