{"id":"W4390984960","doi":"10.1021/acssynbio.3c00408","title":"pUdOs: Concise Plasmids for Bacterial and Mammalian Cells","year":2024,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; Canada Research Coordinating Committee; Canadian Institutes of Health Research; Government of Ontario; University of Ottawa","keywords":"Plasmid; Synthetic biology; Computational biology; Biology; Bacterial genetics; Bacteria; Genetics; Escherichia coli; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001982141,0.001917989,0.001924604,0.002680014,0.001861282,0.001768984,0.00412064,0.001550837,0.02833816],"category_scores_gemma":[0.002092411,0.002607761,0.001092714,0.002695535,0.0008862444,0.001165053,0.0019221,0.003686192,0.04057323],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001250167,"about_ca_system_score_gemma":0.001261775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001350195,"about_ca_topic_score_gemma":0.004214611,"domain_scores_codex":[0.9976432,0.0003950939,0.0003740956,0.0004126824,0.0008573356,0.0003175708],"domain_scores_gemma":[0.9988085,0.0003098004,0.0001441519,0.0003519022,0.0002090849,0.0001765499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001015316,0.0003668724,0.000449799,0.001757552,0.0000729106,0.0005420872,0.0005429122,0.001133535,0.8657294,0.01168036,0.06351627,0.05319304],"study_design_scores_gemma":[0.0002918293,0.0003004481,0.001242688,0.0001657162,0.00005675136,0.0008648034,0.00007122778,0.002273552,0.4417351,0.001628754,0.5512547,0.0001144624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.04038017,0.005758923,0.7387267,0.001134007,0.001509195,0.008464818,0.1399584,0.03668458,0.0273832],"genre_scores_gemma":[0.07793674,0.006148166,0.5336027,0.0005545177,0.0002546742,0.01109233,0.2845589,0.0101592,0.07569283],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02833816,"threshold_uncertainty_score":0.09480059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009615109642987984,"score_gpt":0.2466688278776044,"score_spread":0.2370537182346164,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}