{"id":"W4391004795","doi":"10.1136/bmjopen-2023-083239","title":"Evaluating the impact of a SIMPlified LaYered consent process on recruitment of potential participants to the <i>Staphylococcus aureus</i> Network Adaptive Platform trial: study protocol for a multicentre pragmatic nested randomised clinical trial (SIMPLY-SNAP trial)","year":2024,"lang":"en","type":"article","venue":"BMJ Open","topic":"Ethics in Clinical Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; McMaster University; Sinai Health System; Sunnybrook Health Science Centre; McGill University Health Centre; Institute of Health Services and Policy Research; Health Sciences Centre; Toronto East General Hospital; University of Toronto","funders":"University of Toronto; Canadian Institutes of Health Research; Clinical Trials Fund, Canadian Institutes of Health Research","keywords":"Medicine; Protocol (science); Informed consent; Randomized controlled trial; Staphylococcus aureus; Alternative medicine; Surgery; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.211326,0.003935194,0.004117708,0.002702203,0.002802333,0.004572458,0.002905034,0.009538474,0.05511687],"category_scores_gemma":[0.2800153,0.002881988,0.004521254,0.002994616,0.004328747,0.006055349,0.003218881,0.00668972,0.01425452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006376433,"about_ca_system_score_gemma":0.0267929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001377241,"about_ca_topic_score_gemma":0.00309752,"domain_scores_codex":[0.8080829,0.1547939,0.02017531,0.004690079,0.008384185,0.00387372],"domain_scores_gemma":[0.8421976,0.07850233,0.03057354,0.0198331,0.02017076,0.008722689],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.5373017,0.0119005,0.003684794,0.09318712,0.002902112,0.0009631455,0.008085215,0.007727726,0.004858328,0.03863528,0.1104594,0.1802946],"study_design_scores_gemma":[0.6528394,0.05658614,0.009435853,0.04338206,0.002022047,0.0004230598,0.001383255,0.01699844,0.004988563,0.03832004,0.1728565,0.0007646452],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.001363054,0.00009832891,0.003346713,0.0004408322,0.0003154649,0.9929757,0.0005797388,0.00007632258,0.0008038635],"genre_scores_gemma":[0.001397049,0.00003907879,0.004495901,0.0001538834,0.00002300687,0.9937127,0.00005048633,0.000005363113,0.0001224582],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.788674,"threshold_uncertainty_score":0.9725755,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.893749143142649,"score_gpt":0.7487040355512593,"score_spread":0.1450451075913897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}