{"id":"W4391023727","doi":"10.1021/acsinfecdis.3c00407","title":"Hfe Permease and <i>Haemophilus influenzae</i> Manganese Homeostasis","year":2024,"lang":"en","type":"article","venue":"ACS Infectious Diseases","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Infection and Immunity; National Cancer Institute; National Health and Medical Research Council; Australian Research Council; Medical Research Council; Directorate for Biological Sciences; Australian Synchrotron; Government of Western Australia; University of Melbourne; University of Technology Sydney; Australian Government; University of Queensland; National Computational Infrastructure","keywords":"Haemophilus influenzae; Virulence; Microbiology; Biology; Superoxide dismutase; Manganese; Permease; Reactive oxygen species; Gene; Oxidative stress; Transporter; Chemistry; Cell biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006389205,0.0002213631,0.0002234498,0.000190363,0.0003083152,0.0001486434,0.0000760881,0.000156346,0.0007424534],"category_scores_gemma":[0.00009468398,0.000187767,0.0001040081,0.0002546072,0.0001521804,0.0002899568,0.00009746895,0.0001877978,0.0006785042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003971842,"about_ca_system_score_gemma":0.00006279106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002004494,"about_ca_topic_score_gemma":0.00004035446,"domain_scores_codex":[0.9990529,0.00008640801,0.0001993678,0.000356441,0.00001805912,0.0002868659],"domain_scores_gemma":[0.9994519,0.0001574798,0.00003211871,0.0002396952,0.00005696904,0.00006184421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000482788,0.001713934,0.3172834,0.001398317,0.002859281,0.000251998,0.001753127,0.00003547243,0.2453958,0.02092438,0.1270152,0.2808863],"study_design_scores_gemma":[0.002584329,0.0006985419,0.170698,0.0002932802,0.0009361345,0.002038805,0.0002667693,0.00001181717,0.01035316,0.004914016,0.8060512,0.001153954],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9638173,0.0322949,0.00001340423,0.0002279162,0.001804145,0.0001821136,0.0002279179,0.0006420137,0.0007902772],"genre_scores_gemma":[0.997486,0.001241137,0.00000169974,0.0002583727,0.0002005699,0.00006003172,0.0001088724,0.00003109967,0.0006122095],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.679036,"threshold_uncertainty_score":0.8721026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009904988265544333,"score_gpt":0.2501584894372249,"score_spread":0.2402535011716806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}