{"id":"W4391052563","doi":"10.1007/s00395-023-01023-z","title":"Macrophage profiling in atherosclerosis: understanding the unstable plaque","year":2024,"lang":"en","type":"review","venue":"Basic Research in Cardiology","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":84,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Macrophage; Immune system; Phenotype; Monocyte; Macrophage polarization; Immunology; Foam cell; Inflammation; Biology; Cell; Medicine; Genetics; Gene; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.008821622,0.0005665956,0.002374224,0.001256428,0.0002705767,0.00007834245,0.001465106,0.0016915,0.0001424638],"category_scores_gemma":[0.0002841978,0.0003699373,0.0005379731,0.001889687,0.001442424,0.00007183551,0.001039648,0.007068148,0.001889762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002952549,"about_ca_system_score_gemma":0.001399073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002294965,"about_ca_topic_score_gemma":0.00009828521,"domain_scores_codex":[0.9888011,0.006916025,0.00108034,0.001170673,0.000160554,0.001871371],"domain_scores_gemma":[0.9957379,0.002841332,0.0001443469,0.001184266,0.00006156701,0.00003058179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004237039,0.0002914703,0.0007476031,0.06717042,0.004812473,0.003099107,0.002549263,0.0002549164,0.001613451,0.06658991,0.08655186,0.7658958],"study_design_scores_gemma":[0.0005398722,0.00009226032,0.000007172541,0.01059368,0.0001466808,0.0002966282,0.0008959622,0.00000234491,0.00004773962,0.002280927,0.9847338,0.0003629153],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004547602,0.9860055,0.00004125993,0.0001773294,0.00317807,0.002142198,0.0001053258,0.00005685032,0.008247957],"genre_scores_gemma":[0.003349313,0.9921833,0.00001270749,0.00002614085,0.0002209864,0.001551989,0.0001589263,0.0001313357,0.00236536],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.898182,"threshold_uncertainty_score":0.9998752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3406295767302182,"score_gpt":0.4462691593221857,"score_spread":0.1056395825919675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}