{"id":"W4391088738","doi":"10.1161/circheartfailure.123.010676","title":"Hierarchical End Points in Prior Heart Failure Trials and the HEART-FID Trial","year":2024,"lang":"en","type":"review","venue":"Circulation Heart Failure","topic":"Heart Failure Treatment and Management","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute; Canadian VIGOUR Centre","funders":"National Heart, Lung, and Blood Institute","keywords":"Medicine; Randomized controlled trial; Heart failure; Clinical endpoint; Clinical trial; Intensive care medicine; End point; Physical therapy; Internal medicine; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.005093178,0.0009625863,0.005561096,0.0009014888,0.0002399677,0.0003113826,0.0001731062,0.0008887585,0.0006134413],"category_scores_gemma":[0.001263518,0.0005768256,0.001832705,0.001036676,0.0003484942,0.0001873803,0.0002102297,0.001646183,0.000795691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003331812,"about_ca_system_score_gemma":0.0007461251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008437377,"about_ca_topic_score_gemma":0.0001215363,"domain_scores_codex":[0.9923158,0.002396458,0.00235012,0.001276468,0.0009250699,0.0007360629],"domain_scores_gemma":[0.996375,0.001791838,0.000310341,0.001044799,0.00009016043,0.0003878538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.007646187,0.001026885,0.0004268134,0.03849621,0.003349507,0.0002772599,0.001154952,0.000005219922,0.0000183366,0.0109739,0.6434804,0.2931444],"study_design_scores_gemma":[0.02744113,0.0002232867,0.0001070641,0.007846479,0.003839377,0.000343716,0.00005555801,0.00003871957,7.950991e-7,0.0004433032,0.9592068,0.0004537975],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003174999,0.8619595,0.00001996571,0.1214473,0.0008117072,0.01500908,0.00005550412,0.0002396039,0.0001398729],"genre_scores_gemma":[0.003892033,0.9708622,0.008724286,0.002693601,0.005312849,0.003780574,0.001287303,0.0004440293,0.003003129],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.3157265,"threshold_uncertainty_score":0.9999823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07263803088538773,"score_gpt":0.3726316284653454,"score_spread":0.2999935975799577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}