{"id":"W4391111056","doi":"10.3390/biomedicines12010237","title":"Genetic and Epigenetic Profiles of Polycystic Ovarian Syndrome and In Vitro Bisphenol Exposure in a Human Granulosa Cell Model","year":2024,"lang":"en","type":"article","venue":"Biomedicines","topic":"Ovarian function and disorders","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; CReATe Fertility Centre; University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Office for Victims of Crime; University of Guelph","keywords":"Polycystic ovary; Epigenetics; Internal medicine; Endocrinology; microRNA; Biology; Pathophysiology; Ovary; Granulosa cell; Gene; Genetics; Medicine; Insulin resistance; Obesity","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002051874,0.0001584143,0.0002574231,0.0003356934,0.0001869677,0.0003236296,0.0001092188,0.0002715494,0.001333204],"category_scores_gemma":[0.0001961911,0.0001516185,0.0003473485,0.0003789555,0.0002358705,0.00007422742,0.0002394646,0.0003178777,0.0002365633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002339502,"about_ca_system_score_gemma":0.0002741751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002276416,"about_ca_topic_score_gemma":0.00304882,"domain_scores_codex":[0.9997848,0.00004488484,0.00001923862,0.00005732854,0.00006474404,0.00002918643],"domain_scores_gemma":[0.9998964,0.00002165928,0.00002407104,0.00002188264,0.00002024406,0.00001572871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001284799,0.0001806133,0.01456735,0.000109302,0.00007064459,0.0002948773,0.0002173025,0.0003271561,0.9779825,0.000155188,0.0001815743,0.004628718],"study_design_scores_gemma":[0.0001329705,0.00307645,0.2677577,0.00003528275,0.0003918127,0.001581937,0.0009328995,0.002867612,0.7121457,0.0004199728,0.01060832,0.00004946531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953579,0.001053889,0.001629299,0.00006971337,0.00002697294,0.00005059519,0.001030132,0.00002172112,0.0007597357],"genre_scores_gemma":[0.9934478,0.001239183,0.001631952,0.0001288523,0.000009000229,0.0001389493,0.001654669,0.000008845817,0.001740601],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002276416,"threshold_uncertainty_score":0.004526317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01178051077338029,"score_gpt":0.2428615038040201,"score_spread":0.2310809930306398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}