{"id":"W4391162307","doi":"10.1093/ecco-jcc/jjad212.0639","title":"P509 Upadacitinib improves symptomatic responses in patients with moderately to severely active Crohn’s disease","year":2024,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Crohn's disease; Medicine; Internal medicine; Gastroenterology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001312013,0.0003519115,0.001303326,0.0002339899,0.0002170325,0.0005912709,0.0002409321,0.0002443805,0.00225189],"category_scores_gemma":[0.001468458,0.0001285801,0.001269831,0.0002671879,0.0002233022,0.0003929783,0.0003630671,0.0006844985,0.0002300737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000253302,"about_ca_system_score_gemma":0.0004946499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003349459,"about_ca_topic_score_gemma":0.001261008,"domain_scores_codex":[0.9993949,0.000304576,0.00008482028,0.00007434042,0.00005964506,0.00008164643],"domain_scores_gemma":[0.9990883,0.0002969293,0.0002383186,0.00005657405,0.00006340205,0.0002565534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.606612,0.008651052,0.06347477,0.002809047,0.004892767,0.0004321643,0.0002236504,0.002705394,0.03831183,0.0002127777,0.004825307,0.2668493],"study_design_scores_gemma":[0.09565097,0.4353867,0.4392764,0.0005507534,0.004609182,0.001293778,0.0003047301,0.004287076,0.00890472,0.0005337001,0.009105407,0.00009666746],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918997,0.004926805,0.0002453884,0.0002097794,0.00006128717,0.000300698,0.0006379236,0.00003303415,0.001685494],"genre_scores_gemma":[0.9979924,0.0005662247,0.0003509815,0.0001987605,0.00004192136,0.0001128167,0.0004478987,0.000002790928,0.0002861927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00225189,"threshold_uncertainty_score":0.007533312,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005277523906783461,"score_gpt":0.2346321326638211,"score_spread":0.2293546087570376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}