{"id":"W4391162367","doi":"10.1093/ecco-jcc/jjad212.0093","title":"DOP53 Long-term Efficacy and Safety of Risankizumab in Patients With Moderate to Severe Crohn's Disease up to 3 Years of Treatment: Results From the FORTIFY Open-Label Long-term Extension","year":2024,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Crohn's disease; Term (time); Medicine; Pediatrics; Open label; Crohn disease; Disease; Internal medicine; Adverse effect; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002088292,0.0003774902,0.001220134,0.0001924604,0.0002095508,0.0007044151,0.0002824568,0.0006020029,0.001723329],"category_scores_gemma":[0.001285191,0.0001660518,0.001401406,0.0002721749,0.0002687871,0.0005033274,0.0003072942,0.0008890667,0.0003749873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003938578,"about_ca_system_score_gemma":0.0003702368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004942038,"about_ca_topic_score_gemma":0.001500033,"domain_scores_codex":[0.999209,0.0003564245,0.00008879226,0.0001152344,0.0001171321,0.0001135566],"domain_scores_gemma":[0.9987264,0.0002856721,0.0005171367,0.00008952746,0.0001599611,0.0002211907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6175812,0.006654383,0.09551294,0.002991028,0.005699066,0.0004334444,0.0003134739,0.001838883,0.03950291,0.0001905961,0.005744162,0.2235379],"study_design_scores_gemma":[0.1467762,0.3660497,0.4492158,0.0005051774,0.008383191,0.0009938458,0.0002267601,0.001832725,0.00866614,0.0002824286,0.01695381,0.000114273],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819904,0.01354107,0.0002488052,0.000276374,0.00007634689,0.0002058523,0.001883452,0.00003095408,0.001746662],"genre_scores_gemma":[0.9941655,0.001763059,0.0002683297,0.000348654,0.000135962,0.0001362962,0.002383112,0.000004998727,0.0007939958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002088292,"threshold_uncertainty_score":0.01104409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01286249779609717,"score_gpt":0.2691066486622696,"score_spread":0.2562441508661725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}