{"id":"W4391163063","doi":"10.1093/ecco-jcc/jjad212.0670","title":"P540 Non-serious adverse events in patients with ulcerative colitis receiving etrasimod: An analysis of the phase 2 OASIS and phase 3 ELEVATE UC 52 and ELEVATE UC 12 clinical trials","year":2024,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Ulcerative colitis; Phase (matter); Medicine; Adverse effect; Phases of clinical research; Clinical trial; Internal medicine; Gastroenterology; Intensive care medicine; Disease; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01164865,0.0008829008,0.003405283,0.0008284438,0.0003129686,0.001238861,0.0006486922,0.001033612,0.002767212],"category_scores_gemma":[0.01029667,0.0004245712,0.006035828,0.001536867,0.0005698854,0.001017346,0.000637399,0.001377334,0.0002904379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005022989,"about_ca_system_score_gemma":0.000826948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002375381,"about_ca_topic_score_gemma":0.0006608489,"domain_scores_codex":[0.9899098,0.006427805,0.001328379,0.0009553332,0.001088293,0.0002905148],"domain_scores_gemma":[0.989354,0.005467818,0.00344847,0.0005340247,0.0005466548,0.000649051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8180628,0.001835794,0.08188033,0.00634004,0.03681894,0.0003688495,0.0001358682,0.001062681,0.005004233,0.0001423382,0.001781075,0.04656698],"study_design_scores_gemma":[0.2995032,0.1901816,0.4468971,0.0007496992,0.04741249,0.001262189,0.0002504606,0.002772006,0.001621758,0.0005727457,0.008604219,0.0001725025],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9466304,0.04301995,0.001300515,0.0003508732,0.0002037488,0.0030492,0.003681385,0.00005076107,0.001713107],"genre_scores_gemma":[0.9866635,0.006096532,0.0009581189,0.0004846251,0.0002915304,0.00180827,0.003116338,0.00001848906,0.0005625992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01164865,"threshold_uncertainty_score":0.06160474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01697580414320914,"score_gpt":0.3405112745898375,"score_spread":0.3235354704466283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}