{"id":"W4391163189","doi":"10.1093/ecco-jcc/jjad212.0106","title":"DOP66 INSPIRE: Preliminary data from an observational post-marketing registry on the effectiveness and safety of darvadstrocel in patients with Crohn’s Disease and complex perianal fistulas","year":2024,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Anorectal Disease Treatments and Outcomes","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta Hospital; University of Alberta","funders":"","keywords":"Medicine; Cohort; Adverse effect; Crohn's disease; Observational study; Internal medicine; Clinical Practice; Clinical trial; Surgery; Disease; Physical therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00687943,0.0003139294,0.0007707627,0.0006016413,0.0002999484,0.001010099,0.0004123487,0.0006153818,0.005182593],"category_scores_gemma":[0.01343346,0.0002067832,0.001226892,0.00105028,0.0003694073,0.0009388524,0.0006811464,0.0007954805,0.0008164085],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004012081,"about_ca_system_score_gemma":0.0006153387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003187165,"about_ca_topic_score_gemma":0.0005785291,"domain_scores_codex":[0.9927611,0.003459254,0.001134401,0.0007795054,0.001508274,0.0003574849],"domain_scores_gemma":[0.9752598,0.007463558,0.01303107,0.001925302,0.001391389,0.0009287281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.06056963,0.00235769,0.8791382,0.001162842,0.002220616,0.0003717446,0.0002979235,0.0004902498,0.002062278,0.0003350326,0.005414317,0.04557939],"study_design_scores_gemma":[0.008149931,0.02232894,0.9518459,0.0002843817,0.001573806,0.001416018,0.0002583139,0.001197809,0.001475165,0.0002795731,0.01113041,0.00005965139],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9719392,0.002279769,0.001023313,0.000345121,0.00003241783,0.0008009857,0.01831369,0.00003525804,0.005230223],"genre_scores_gemma":[0.9774348,0.000643369,0.001000229,0.0004330753,0.0001300033,0.0008670453,0.01860267,0.00001819533,0.0008705932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00687943,"threshold_uncertainty_score":0.03638238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03225788444766219,"score_gpt":0.292535289678542,"score_spread":0.2602774052308798,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}