{"id":"W4391163392","doi":"10.7554/elife.92307.2","title":"Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter","year":2024,"lang":"en","type":"preprint","venue":"eLife","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"Marsden Fund; Biomolecular Interaction Centre, University of Canterbury; Science for Life Laboratory; Umeå Universitet; Australian Cancer Research Foundation; Royal Society Te Apārangi; Knut och Alice Wallenbergs Stiftelse; Stockholms Universitet; Canterbury Medical Research Foundation; Kempestiftelserna; Australian Synchrotron; Kempe Foundation; Australian Nuclear Science and Technology Organisation; Australian Institute of Nuclear Science and Engineering","keywords":"Periplasmic space; Trap (plumbing); Haemophilus influenzae; Transporter; Chemistry; Biophysics; Biology; Biochemistry; Physics; Escherichia coli; Gene; Meteorology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008578238,0.0001656725,0.0001160611,0.00008820858,0.0001798487,0.0002099595,0.0002600242,0.0003173932,0.0004422381],"category_scores_gemma":[0.0001692787,0.00009430241,0.0001763792,0.0001304357,0.000129928,0.0001319075,0.0001394146,0.0002661521,0.0002004595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003249457,"about_ca_system_score_gemma":0.0001399827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002739708,"about_ca_topic_score_gemma":0.001449993,"domain_scores_codex":[0.9999619,0.000005458816,0.000002376811,0.000008375779,0.00001423994,0.000007738059],"domain_scores_gemma":[0.999952,0.000008480651,0.00001010053,0.000005015394,0.00001066563,0.00001385516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001167116,0.00003198167,0.001264753,0.00004066958,0.00001113228,0.0002294959,0.0000556434,0.001933309,0.995112,0.0001703957,0.0001301845,0.0009036559],"study_design_scores_gemma":[0.00006068248,0.0004030721,0.07303278,0.00002097947,0.00005190349,0.001077949,0.0003758308,0.07311045,0.8452229,0.0004437461,0.00615553,0.00004422093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981452,0.000174106,0.001019456,0.0000646991,0.000005062268,0.000003585922,0.000230574,0.00002332676,0.000333837],"genre_scores_gemma":[0.9958221,0.0002097164,0.00221755,0.00002382295,0.000003854127,0.000005984197,0.001131445,0.0000159211,0.0005697406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002739708,"threshold_uncertainty_score":0.005447567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0123115942454461,"score_gpt":0.2689261354675226,"score_spread":0.2566145412220766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}