{"id":"W4391187782","doi":"10.1017/cjn.2024.8","title":"Genetic Association Studies in Restless Legs Syndrome: Risk Variants & Ethnic Differences","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques","topic":"Restless Legs Syndrome Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Medical Research Council; Medical Research Council","keywords":"Restless legs syndrome; Genome-wide association study; Odds ratio; Genetic association; Genetics; Meta-analysis; Candidate gene; Medicine; Genetic model; Bioinformatics; Biology; Internal medicine; Genotype; Single-nucleotide polymorphism; Gene; Psychiatry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009024296,0.0006552287,0.003038908,0.005681719,0.0003680572,0.001407531,0.0009031408,0.001087289,0.003956993],"category_scores_gemma":[0.02604442,0.0003243941,0.003961305,0.01172937,0.0007955832,0.001146286,0.0007069086,0.0007372891,0.0002956041],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007797245,"about_ca_system_score_gemma":0.002317746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002926533,"about_ca_topic_score_gemma":0.006715348,"domain_scores_codex":[0.993257,0.002319739,0.002547652,0.0008849603,0.0008303017,0.0001603333],"domain_scores_gemma":[0.9676259,0.02535297,0.005405368,0.0004651465,0.001021562,0.0001290493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"observational","study_design_scores_codex":[0.001041674,0.00005426606,0.0700332,0.6869583,0.05304408,0.001182937,0.0008012194,0.0006237208,0.001150634,0.001969811,0.008175459,0.1749648],"study_design_scores_gemma":[0.001193084,0.0005683935,0.2074652,0.4646858,0.2174922,0.005936113,0.001466049,0.0007431366,0.00104624,0.008124879,0.09112714,0.0001518253],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.006608906,0.9901376,0.0005837252,0.00088432,0.0001763109,0.0001108289,0.0009047266,0.00001119349,0.000582383],"genre_scores_gemma":[0.1492833,0.8405923,0.004996171,0.002287155,0.0005070053,0.000679141,0.001245933,0.00001958971,0.0003893436],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.009024296,"threshold_uncertainty_score":0.04772562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1504065311625514,"score_gpt":0.3856093735966267,"score_spread":0.2352028424340753,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}