{"id":"W4391187782","doi":"10.1017/cjn.2024.8","title":"Genetic Association Studies in Restless Legs Syndrome: Risk Variants & Ethnic Differences","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques","topic":"Restless Legs Syndrome Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Medical Research Council; Medical Research Council","keywords":"Restless legs syndrome; Genome-wide association study; Odds ratio; Genetic association; Genetics; Meta-analysis; Candidate gene; Medicine; Genetic model; Bioinformatics; Biology; Internal medicine; Genotype; Single-nucleotide polymorphism; Gene; Psychiatry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","sts","research_integrity"],"consensus_categories":["sts"],"category_scores_codex":[0.009672881,0.0003803843,0.0009010813,0.002497501,0.001372166,0.0008693032,0.001522213,0.0003223238,0.0002134602],"category_scores_gemma":[0.01219352,0.0002436962,0.0002972306,0.003474841,0.005107592,0.0009613979,0.00009981498,0.002978029,0.00002374769],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001172394,"about_ca_system_score_gemma":0.005746631,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002862925,"about_ca_topic_score_gemma":0.1130228,"domain_scores_codex":[0.9924611,0.002078955,0.001231127,0.0007520575,0.001678198,0.001798503],"domain_scores_gemma":[0.9939846,0.002766881,0.0006354955,0.0002031683,0.0005915892,0.001818312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0000497571,0.00003316691,0.9566847,0.00005061696,0.00006400039,0.03728499,0.0006774709,0.0008022913,0.00003284469,0.0001560346,0.0008532376,0.003310868],"study_design_scores_gemma":[0.000282707,0.02254449,0.8937114,0.000351525,0.00008214826,0.0699439,0.0002935194,0.001010381,0.000007676455,0.01058302,0.0009447271,0.0002445421],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9724426,0.01857736,0.00001555917,0.006314716,0.001558737,0.0002474571,0.00001429838,0.00002863036,0.0008006063],"genre_scores_gemma":[0.9894188,0.008266042,0.001160933,0.0006782719,0.0002593539,0.000006655733,2.333847e-7,0.00001834963,0.0001913804],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1101599,"threshold_uncertainty_score":0.9999279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1504065311625514,"score_gpt":0.3856093735966267,"score_spread":0.2352028424340753,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}