{"id":"W4391215023","doi":"10.1093/ibd/izae004","title":"Extended Induction and Prognostic Indicators of Response in Patients Treated with Mirikizumab with Moderately to Severely Active Ulcerative Colitis in the LUCENT Trials","year":2024,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; UCB Pharma; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Ulcerative colitis; Medicine; Internal medicine; Gastroenterology; Colitis; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007622454,0.0005445791,0.0009555666,0.0002849504,0.0002408991,0.0007914199,0.0005233363,0.0004933228,0.001229119],"category_scores_gemma":[0.003900949,0.0001820877,0.001228988,0.000413439,0.0003209803,0.0007020255,0.0005185676,0.001222919,0.0001911809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004106786,"about_ca_system_score_gemma":0.0004610505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000276922,"about_ca_topic_score_gemma":0.0007615025,"domain_scores_codex":[0.9974548,0.00195532,0.0001106118,0.0001593189,0.0001578751,0.0001620546],"domain_scores_gemma":[0.9956677,0.00160514,0.001830879,0.000243223,0.0001660447,0.000487045],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2714759,0.001348306,0.65367,0.0008870732,0.004505683,0.0001861262,0.0002191838,0.002677689,0.002062794,0.0002691303,0.002609357,0.0600888],"study_design_scores_gemma":[0.01613849,0.02573689,0.944188,0.0002065433,0.002423194,0.0003544341,0.0001074899,0.004718414,0.0008209711,0.0004037194,0.004840737,0.00006109223],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931613,0.004604931,0.0002816771,0.0003940015,0.00002150421,0.000132834,0.0006170602,0.00002133591,0.0007652523],"genre_scores_gemma":[0.9969139,0.0004863395,0.0005333378,0.0001740393,0.00006667542,0.0001743743,0.001350029,0.000005339258,0.0002959016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007622454,"threshold_uncertainty_score":0.04031187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009936719629544667,"score_gpt":0.2537035102998549,"score_spread":0.2437667906703103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}