{"id":"W4391225080","doi":"10.3390/cells13030218","title":"Aberrant MET Receptor Tyrosine Kinase Signaling in Glioblastoma: Targeted Therapy and Future Directions","year":2024,"lang":"en","type":"review","venue":"Cells","topic":"Liver physiology and pathology","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Receptor tyrosine kinase; Cancer research; Biology; Hepatocyte growth factor; Targeted therapy; Hepatocyte Growth Factor Receptor; Metastasis; C-Met; Tyrosine kinase; Cancer; Signal transduction; Medicine; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001720691,0.0007176676,0.001244722,0.001117801,0.000263829,0.001339031,0.0009580704,0.0020038,0.002459213],"category_scores_gemma":[0.0006710373,0.0002716944,0.0006174666,0.0008373592,0.0008206517,0.002152918,0.0007222941,0.002422264,0.001244643],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001294824,"about_ca_system_score_gemma":0.001670467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001162859,"about_ca_topic_score_gemma":0.003326772,"domain_scores_codex":[0.9997082,0.00007371321,0.00002605379,0.00004659914,0.00006248572,0.0000828531],"domain_scores_gemma":[0.999514,0.0001227458,0.00006836018,0.00001871358,0.0001511729,0.0001249229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001329938,0.0007645507,0.001606842,0.004113857,0.0001606163,0.0008468488,0.0001570179,0.00165093,0.01194542,0.01262839,0.055873,0.9089224],"study_design_scores_gemma":[0.0007592941,0.005153398,0.00757682,0.005762415,0.0007226348,0.004445564,0.0006276099,0.005537252,0.008849512,0.03038043,0.9300295,0.0001555552],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002911556,0.9828452,0.0009662184,0.01082526,0.0004660342,0.00002354459,0.00006166462,0.0000663471,0.001834061],"genre_scores_gemma":[0.02065249,0.9690936,0.002030914,0.004533172,0.001682059,0.0000785642,0.0001840825,0.00001530205,0.001729883],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002459213,"threshold_uncertainty_score":0.009394646,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03205105414466499,"score_gpt":0.3054615068935274,"score_spread":0.2734104527488624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}