{"id":"W4391232154","doi":"10.1038/s41562-023-01807-2","title":"Reproduction and replication at scale","year":2024,"lang":"en","type":"letter","venue":"Nature Human Behaviour","topic":"Gene expression and cancer classification","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Government of Canada; Open Philanthropy Project; University of Ottawa; Alfred P. Sloan Foundation","keywords":"Replication (statistics); Reproduction; Scale (ratio); Biology; Computer science; Geography; Genetics; Virology; Cartography","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0001428837,0.0002119862,0.000133017,0.00009612813,0.0001384196,0.00005464375,0.0001575297,0.001834801,0.00004563124],"category_scores_gemma":[0.00001967359,0.0002010162,0.00008515573,0.00007379762,0.00005980574,0.000002614839,0.0001462281,0.001214836,0.0000258676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005700512,"about_ca_system_score_gemma":0.00002840484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005319515,"about_ca_topic_score_gemma":0.00001300548,"domain_scores_codex":[0.9981669,0.00004498269,0.0001892772,0.001243458,0.0001969852,0.0001583803],"domain_scores_gemma":[0.9985045,0.000001793339,0.0001263676,0.001240025,0.00009030959,0.00003699323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005722362,0.000007069528,0.0005186578,0.00004026603,0.000009161667,0.000003905375,0.00001424552,6.390701e-8,0.2270425,0.000007570055,0.7717062,0.0006446312],"study_design_scores_gemma":[0.00009518901,0.00004783969,0.004797948,0.00003606785,0.0000685509,0.00005029315,0.000006449299,3.784152e-7,0.08439933,0.00008452101,0.9102032,0.0002102342],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5008876,0.01995842,0.00002203211,0.4718952,0.002476637,0.0008086927,0.0001324052,0.0001614192,0.003657616],"genre_scores_gemma":[0.4318675,0.0007556682,0.0002212415,0.2297601,0.01725526,0.0003411409,0.01375121,0.0002246639,0.3058231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3021655,"threshold_uncertainty_score":0.9994611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01358717913179241,"score_gpt":0.2980346433643018,"score_spread":0.2844474642325094,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}